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Name Acetyl chloride
CAS 75-36-5
EINECS(EC#) 200-865-6
Molecular Formula C2H3ClO
MDL Number MFCD00000719
Molecular Weight 78.5
MOL File 75-36-5.mol

Chemical Properties


Acetic chloride is a colourless to light yellow liquid with a pungent and choking odour. Acetic chloride is highly flammable and reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. Along with air, acetic chloride may form an explosive mixture. It is incompatible with water, alcohols, amines, strong bases, strong oxidising agents, and most common metals. On decomposition when heated, acetic chloride produces carbon monoxide, carbon dioxide, hydrogen chloride, and phosgene.

Appearance Acetyl chloride is a highly flammable, colorless, fuming liquid with a pungent odor
Melting point  -112 °C
Boiling point  52 °C(lit.)
density  1.104 g/mL at 25 °C(lit.)
vapor density  2.7 (vs air)
vapor pressure  11.69 psi ( 20 °C)
refractive index  n20/D 1.389(lit.)
Fp  40 °F
storage temp.  Store at RT
solubility  Miscible with acetone, chloroform, glacial acetic acid, petroleum ether, ether and benzene.
form  Liquid
Specific Gravity approximate 1.11
color  Clear colorless
Odor Strong pungent odor
Stability: Stability Highly flammable. Reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. May form an explosive mixture with air. Note low flash point. Incompatible with water, alcohols, amines, strong bases, strong oxidizing agents, most common metals.
explosive limit 7.3-19%(V)
Water Solubility  Decomposes violently in water
Sensitive  Moisture Sensitive
Merck  14,85
BRN  605303
CAS DataBase Reference 75-36-5(CAS DataBase Reference)
NIST Chemistry Reference Acetyl chloride(75-36-5)
EPA Substance Registry System 75-36-5(EPA Substance)

Safety Data

Hazard Codes  F,C
Risk Statements 

R11:Highly Flammable.
R14:Reacts violently with water.
R34:Causes burns.

Safety Statements 

S9:Keep container in a well-ventilated place .
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S1/2:Keep locked up and out of the reach of children .

RIDADR  UN 1717 3/PG 2
WGK Germany  1
RTECS  AO6390000
Autoignition Temperature 390 °C DIN 51794
HazardClass  3
PackingGroup  II
HS Code  29159080
storage Acetic chloride should be stored in a segregated and approved area, away from incompatibles such as oxidizing agents, alkalis and moisture. The container of acetic chloride should be kept in a cool, well-ventilated area, tightly sealed until ready for use. Users should avoid all possible sources of ignition, i.e., spark or flames.
Safety Profile

Poison by inhalation. Moderately toxic by ingestion. A human systemic irritant by inhalation. Violent hydrolysis reaction with water or steam produces heat, acetic acid, HCl, and other corrosive chlorides. May decompose during preparation. Dangerous fire hazard when exposed to heat or flame. Explosion hazard by spontaneous chemical reaction with dimethyl sulfoxide or ethanol. Also incompatible with Pcb. When heated to decomposition it emits highly toxic fumes of phosgene and Cl-. To fight fire, use CO2 or dry chemical. See also CHLORIDES

Hazardous Substances Data 75-36-5(Hazardous Substances Data)

Hazard Information

Material Safety Data Sheet(MSDS)

Questions And Answer

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