(1-Methylethyl)benzol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H226：Flüssigkeit und Dampf entzündbar.

  H304：Kann bei Verschlucken und Eindringen in die Atemwege tödlich sein.

  H335：Kann die Atemwege reizen.

  H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P210：Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.

  P233：Behälter dicht verschlossen halten.

  P240：Behälter und zu befüllende Anlage erden.

  P273：Freisetzung in die Umwelt vermeiden.

  P301+P310：BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P331：KEIN Erbrechen herbeiführen.

Cumene Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.

• PHYSIKALISCHE GEFAHREN

  Fließen, Schütten o.ä. kann zu elektrostatischer Aufladung führen.

• CHEMISCHE GEFAHREN

  Reagiert sehr heftig mit Säuren und starken Oxidationsmitteln unter Feuer- und Explosionsgefahr. Bildung explosionsfähiger Peroxide.

• ARBEITSPLATZGRENZWERTE

  TLV: 50 ppm (als TWA); (ACGIH 2005).
  MAK: 20 ppm 250 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(4); Hautresorption; Schwangerschaft: Gruppe C; (DFG 2005).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Inhalation und über die Haut.

• INHALATIONSGEFAHREN

  Beim Verdampfen bei 20°C tritt langsam eine gesundheitsschädliche Kontamination der Luft ein.

• WIRKUNGEN BEI KURZZEITEXPOSITION

  WIRKUNGEN BEI KURZZEITEXPOSITION:
  Die Flüssigkeit reizt die Augen und die Haut. Verschlucken kann zur Aufnahme in der Lunge führen; Gefahr der Aspirationspneumonie. Möglich sind Auswirkungen auf das Zentralnervensystem. Exposition weit oberhalb der Arbeitsplatzgrenzwerte kann zu Bewusstlosigkeit führen.

• WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION

  Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.

• LECKAGE

  Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.

• R-Sätze Betriebsanweisung:

  R10:Entzündlich.
  R37:Reizt die Atmungsorgane.
  R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
  R65:Gesundheitsschädlich: kann beim Verschlucken Lungenschäden verursachen.

• S-Sätze Betriebsanweisung:

  S24:Berührung mit der Haut vermeiden.
  S37:Geeignete Schutzhandschuhe tragen.
  S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
  S62:Bei Verschlucken kein Erbrechen herbeiführen. Sofort ärztlichen Rat einholen und Verpackung oder dieses Etikett vorzeigen.

• Aussehen Eigenschaften

  C9H12; Isopropylbenzol, 2-Phenylpropan. Farblose Flüssigkeit mit aromatischem Geruch.

• Gefahren für Mensch und Umwelt

  Reizt die Atmungsorgane, Augen und die Haut. Wird auch über die Haut aufgenommen. Kann zu Schläfrigkeit, Erregung und Krämpfen bis zur Narkose führen.
  Bildung von Peroxiden möglich. Entzündlich.
  LD₅₀ (oral, Ratte) 1400 mg/kg.

• Schutzmaßnahmen und Verhaltensregeln

  Schutzhandschuhe als kurzzeitiger Spritzschutz.

• Verhalten im Gefahrfall

  Mit flüssigkeitsbindendem Material, z.B. Rench Rapid aufnehmen. Der Entsorgung zuführen. Nachreinigen.
  Kohlendioxid, Pulver, Schaum.
  Brennbar. Dämpfe schwerer als Luft. Mit Luft Bildung explosionsfähiger Gemische.

• Erste Hilfe

  Nach Hautkontakt: Mit reichlich Wasser abwaschen.
  Nach Augenkontakt: Mit reichlich Wasser bei geöffnetem Lidspalt mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
  Nach Einatmen: Frischluft. Arzt hinzuziehen.
  Nach Verschlucken: Reichlich Wasser trinken lassen. Erbrechen auslösen. Arzt hinzuziehen.
  Nach Kleidungskontakt: Kontaminierte Kleidung entfernen.
  Ersthelfer: siehe gesonderten Anschlag

• Sachgerechte Entsorgung

  Als halogenfreie, organische Lösemittelabfälle.

• Beschreibung

  Cumene is a common name for isopropylbenzene, an organic compound. Cumene is a volatile colorless liquid at room temperature with a characteristic sharp, penetrating, aromatic odor. It is insoluble in water but is soluble in alcohol and many other organic solvents. Cumene is structurally a member of the alkyl aromatic family of hydrocarbons, which also includes toluene (methylbenzene) and ethylbenzene.Cumene can be found in crude oil, refined fuels, and is a part of processed highoctane gasoline.
  Cumene is manufactured by reacting benzene with propylene at elevated temperature and pressure in the presence of a catalyst. It is considered an environmental pollutant because it is a natural component of petroleum and is present in tobacco smoke. Cumene vapor can be absorbed by the respiratory tract. Sufficiently high levels of exposure to cumene causes central nervous system (CNS) depression leading to death, internal bleeding of numerous organs, as well as irritation of the eyes and respiratory system, skin, and mucous membranes. Cumene is a high production volume chemical.

• Chemische Eigenschaften

  cumene is oxidized to its hydroperoxide, which is used to produce propene oxide. The alcohol produced is subsequently converted back to cumene over a copper-chromium oxide catalyst to be reused in the process. The advantage of this process is that cumene is easier to hydroperoxidate (more stable).

• Physikalische Eigenschaften

  Colorless liquid with an aromatic odor. Experimentally determined detection and recognition odor threshold concentrations were 40 μg/m³ (8 ppb_v) and 230 μg/m³ (47 ppb_v), respectively (Hellman and Small, 1974). The taste threshold concentration in water is 60 ppb (Young et al., 1996).

• Verwenden

  Around 98% of cumene is used in the production of phenol and its coproduct, acetone, using cumene hydroperoxide as chemical intermediate. However, the demand for cumene is largely dependent on the performance of phenol’s derivatives, which have resulted in healthy growth rates in demand for cumene. It is also used as a starting material in the production of acetophenone, α-methylstyrene, diisopropylbenzene, and dicumylperoxide. Cumene is used as a thinner for paints, lacquers, and enamels. It is also used in the manufacture of acetophenone, methylstyrene, and other chemicals commonly found in home cleaning products. Minor uses of cumene include as a constituent of some petroleum-based solvents, such as naphtha; in gasoline blending diesel fuel and highoctane aviation fuel; and as a raw material for peroxides and oxidation catalysts such as polymerization catalysts for acrylic and polyester-type resins. It is also a good solvent for fats and resins and has been suggested as a replacement for benzene in many of its industrial applications.

• Verwenden

  Raw Material for Phenol, Acetone and Alpha Methyl Styrene production, intermediate for argochemicals

• Verwenden

  Production of phenol, acetone, and α- methylstyrene; solvent.

• Verwenden

  It is used as a solvent and in the productionof phenol, acetone, and acetophenone.

• Definition

  ChEBI: Cumene is an alkylbenzene that is benzene carrying an isopropyl group.

• Allgemeine Beschreibung

  Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

• Air & Water Reaktionen

  Flammable. Insoluble in water.

• Reaktivität anzeigen

  Mixing CUMENE in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, oleum, NFPA 1991.

• Hazard

  Toxic by ingestion, inhalation, and skin absorption; a narcotic. Moderate fire risk. Eye, skin, and upper respiratory tract irritant, and central nervous system impairment. Possible carcinogen.

• Health Hazard

  Cumene is an irritant to the eyes, skin, andupper respiratory system, and a low acutetoxicant. It is narcotic at high concentrations.The narcotic effect is induced slowly andis of longer duration relative to benzeneand toluene (ACGIH 1986). Although thetoxicity may be of same order, the hazardfrom inhalation is low due to its high boilingpoint and low vapor pressure. An exposureto 8000 ppm for 4 hours was lethal to rats.The oral toxicity of cumene was determinedto be low in animals. In addition to narcosis, itcaused gastritis. An LD50 value documentedfor mice is 1400 mg/kg (NIOSH 1986).
  Chronic inhalation toxicity of cumene wasvery low in animals. Repeated exposurescaused congestion in the lungs, liver, andkidney and an increase in the kidney weight.A major portion of cumene absorbed into the body is metabolized in the liver andexcreted. The urinary metabolites constitutedconjugated alcohols or acids.

• Health Hazard

  Narcotic action with long-lasting effects; depressant to central nervous system. Acute (short-term) inhalation exposure to cumene may cause headaches, dizziness, drowsiness, slight incoordination, and unconsciousness in humans. Cumene has a potent central nervous system (CNS) depressant action characterized by a slow induction period and long duration of narcotic effects in animals. Cumene is a skin and eye irritant. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of cumene in humans. Animal studies have reported increased liver, kidney, and adrenal weights from inhalation exposure to cumene. EPA has classified cumene as a Group D, not classifiable as to human carcinogenicity.

• Brandgefahr

  HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

• Chemische Reaktivität

  Reactivity with Water: No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

• Sicherheitsprofil

  Moderately toxic by ingestion. Mdly toxic by inhalation and skincontact. Human systemic effects by inhalation: an antipsychotic, unspecified changes in the sense of smell and respiratory system. An eye and skin irritant. Potential narcotic action. Central nervous system depressant. There is no apparent difference between the toxicity of natural cumene and that derived from petroleum. See also BENZENE and TOLUENE. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. Violent reaction with HNO3, oleum, chlorosulfonic acid. To fight fKe, use foam, CO2, dry chemical.

• mögliche Exposition

  Cumene is used primarily in the manufacture acetone and phenol which are widely used as solvents for paints, laquers, and varnishes and to make plastics. Cumene is used in gasoline blending and as a high-octane gasoline component. It is also found as a component in tobacco smoke.

• mögliche Exposition

  Cumene is a constituent of crude oil and finished fuels. It is released to the environment as a result of its production and processing from petroleum refining, the evaporation and combustion of petroleum products, and by the use of a variety of products containing cumene.
  The most probable route of human exposure is by the inhalation of contaminated air from the evaporation of petroleum products.
  Exposure may also occur through the consumption of contaminated food or water.

• Erste Hilfe

  If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Do not induce vomiting

• Carcinogenicity

  Cumene was not a developmental toxicant in either rats or rabbits after exposure to levels (1200ppm and 2300ppm, respectively) associated with maternal toxicity.9 Most genotoxic tests with cumene have been negative.
  The LD50 for penetration of rabbit skin was 12.3 ml/kg after 14 days.4 Contact of the liquid with the skin causes erythema and irritation. 11 Eye contamination may produce conjunctival irritation.
  It generally is agreed that cumene has no damaging effect on the hematopoietic system, despite its chemical similarity to benzene.5 Furthermore, cumene is not anticipated to be a significant carcinogenic hazard because it is metabolically similar to toluene, a substance that showed no carcinogenic activity in 2-year inhalation studies.

• Source

  As of October 1995, no MCLGs or MCLs have been proposed although isopropylbenzene has been listed for regulation (U.S. EPA, 1996). A DWEL of 400 μg/L was recommended (U.S. EPA, 2000).
  Detected in distilled water-soluble fractions of 94 octane gasoline and Gasohol at concentrations of 0.14 and 0.15 mg/L, respectively (Potter, 1996).
  Thomas and Delfino (1991) equilibrated contaminant-free groundwater collected from Gainesville, FL with individual fractions of three individual petroleum products at 24–25 °C for 24 h. The aqueous phase was analyzed for organic compounds via U.S. EPA approved test method 602. Average isopropylbenzene concentrations reported in water-soluble fractions of unleaded gasoline and kerosene were 235 and 28 μg/L, respectively. When the authors analyzed the aqueous-phase via U.S. EPA approved test method 610, average isopropylbenzene concentrations in water-soluble fractions of unleaded gasoline and kerosene were lower, i.e., 206 and 22 μg/L, respectively. Isopropylbenzene was detected in both water-soluble fractions of diesel fuel but were not quantified.
  Isopropylbenzene was detected in California Phase II reformulated gasoline at a concentration of 830 mg/kg (Schauer et al., 2002).
  Isopropylbenzene naturally occurs in Ceylon cinnamon, cumin, and ginger (1 ppm in rhizome) (Duke, 1992).

• Environmental Fate

  ological. When isopropylbenzene was incubated with Pseudomonas putida, the substrate was converted to ortho-dihydroxy compounds in which the isopropyl part of the compound remained intact (Gibson, 1968). Oxidation of isopropylbenzene by Pseudomonas desmolytica S44B1 and Pseudomonas convexa S107B1 yielded 3-isopropylcatechol and a ring fission product, (+)-2- hydroxy-7-methyl-6-oxooctanoic acid (Jigami et al., 1975).
  Surface Water. Mackay and Wolkoff (1973) estimated an evaporation half-life of 14.2 min from a surface water body that is 25 °C and 1 m deep.
  Photolytic. Major products reported from the photooxidation of isopropylbenzene with nitrogen oxides include nitric acid and benzaldehyde (Altshuller, 1983). A n-hexane solution containing isopropylbenzene and spread as a thin film (4 mm) on cold water (10 °C) was irradiated by a mercury medium pressure lamp. In 3 h, 22% of the applied isopropylbenzene photooxidized into α,α-dimethylbenzyl alcohol, 2-phenylpropionaldehyde, and allylbenzene (Moza and Feicht, 1989).
  A rate constant of 3.7 x 109 L/molecule·sec was reported for the reaction of isopropylbenzene with OH radicals in the gas phase (Darnall et al., 1976). Similarly, a room temperature rate constant of 6.6 x 10^-12 cm³/molecule·sec was reported for the vapor-phase reaction of isopropylbenzene with OH radicals (Atkinson, 1985). At 25 °C, a rate constant of 6.25 x 10^-12 cm³/molecule·sec was reported for the same reaction (Ohta and Ohyama, 1985). Chemical/Physical. Complete combustion in air yields carbon dioxide and water vapor. Isopropylbenzene will not hydrolyze because it does not contain a hydrolyzable functional group.
  The calculated evaporation half-life of isopropylbenzene from surface water 1 m deep at 25 °C is 5.79 h (Mackay and Leinonen, 1975).

• Lager

  Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.May form peroxides in storage. Prior to working with thischemical you should be trained on its proper handling andstorage. Before entering confined space where this chemicalmay be present, check to make sure that an explosive concentration does not exist. Cumene must be stored to avoidcontact with oxidizers, such as permanganates, nitrites, peroxides, chlorates, and perchlorates, since violent reactionsoccur. Store in tightly closed containers in a cool well-ventilated area away from heat. Sources of ignition, such assmoking and open flames, are prohibited where Cumene isused, handled, or stored in a manner that could create apotential fire or explosion hazard. Metal containers involving the transfer of=gallons or more of this chemical shouldbe grounded and bonded. Drums must be equipped withself-closing valves, pressure vacuum bungs, and flamearresters. Use only nonsparking tools and equipment, especially when opening and closing containers of thischemical.

• Versand/Shipping

  UN1918 Cumene, Hazard Class: 3; Labels: 3-Flammable liquid

• Toxicity evaluation

  Cumene is released into the environment as a result of production and processing from petroleum refining and the evaporation and combustion of petroleum products. Cumene also occurs in a variety of natural substances including essential oils from plants and foodstuffs. When released to soil, cumene is expected to biodegrade and may volatilize from the soil surface. Cumene is expected to have low mobility based on its estimated adsorption coefficient (Koc) of 820. Based on Henry’s law constant of 0.0115 atm m³ mol^-1, cumene volatilization from moist soil surfaces is expected to be an important environmental fate and it may volatilize from dry soil surfaces based on its vapor pressure. Cumene is expected to strongly adsorb to soils and is not expected to leach to groundwater.
  When released into the atmosphere, a vapor pressure of 4.5 mmHg at 25°C indicates that cumene exists solely as a vapor in the ambient atmosphere. Cumene in the vapor phase reacts with photochemically generated hydroxyl radicals. The reaction of cumene in the vapor phase with ozone has an estimated half-life of 2.5 days. Cumene may also react with ozone radicals found in the atmosphere but not at an environmentally important rate.

• Inkompatibilitäten

  Vapor may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, 942 Cumene fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Air contact forms cumene hydroperoxide. Attacks rubber. May accumulate static electrical charges, and may cause ignition of its vapors.

• Waste disposal

  Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Cumene Upstream-Materialien And Downstream Produkte

(1-Methylethyl)benzol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(308)Suppliers

98-82-8, Cumene Verwandte Suche: