Basic information Uses The precursor drug of Antihypertensive drug Candesartan---Candesartan cilexetil Candesartan cilexetil tablets Appendix I Appendix II Side effects and adverse reactions Precautions References Safety Related Supplier
Candesartan cilexetil  Structure

Candesartan cilexetil

Chemical Properties

Melting point 168-170?C
Boiling point 843.3±75.0 °C(Predicted)
Density  1.37±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: ≥15mg/mL
pka pKa 3.55 (H2O t=25.0 I=0.025) (Uncertain);5.91(H2O t=25.0 I=0.025) (Uncertain)
form  powder
color  white to beige
λmax 304nm(EtOH)(lit.)
Merck  14,1739
BCS Class 2
InChIKey GHOSNRCGJFBJIB-UHFFFAOYSA-N
SMILES C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C2=C(C(OC(OC(OC3CCCCC3)=O)C)=O)C=CC=C2N=1
CAS DataBase Reference 145040-37-5(CAS DataBase Reference)

Safety Information

Hazard Codes  Xn,N,T
Risk Statements  20/21/22-36/37/38-50-48/20-61
Safety Statements  26-36-61-45-53
WGK Germany  3
RTECS  DD6672500
HS Code  29339953
Toxicity dog,LD50,oral,> 2gm/kg (2000mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 406, 2000.

Usage And Synthesis

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