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Sulfanilic acid

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Sulfanilic acid Basic information
Sulfanilic acid Chemical Properties
  • Melting point:>300 °C(lit.)
  • Density 1.485
  • refractive index 1.5500 (estimate)
  • storage temp. Store below +30°C.
  • solubility 10g/l
  • form solid
  • pka3.24(at 25℃)
  • PH2.5 (10g/l, H2O, 20℃)
  • Water Solubility 0.1 g/100 mL (20 ºC)
  • Merck 14,8926
  • BRN 908765
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • CAS DataBase Reference121-57-3(CAS DataBase Reference)
  • NIST Chemistry ReferenceBenzenesulfonic acid, 4-amino-(121-57-3)
  • EPA Substance Registry SystemSulfanilic acid (121-57-3)
Safety Information
Sulfanilic acid Usage And Synthesis
  • DescriptionSulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.
  • Chemical Propertiesgreyish-white crystals or powder
  • UsesA toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.
  • DefinitionChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.
  • ApplicationAs the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
    It is also used as a standard in combustion analysis.
  • General DescriptionWhite powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).
  • Air & Water ReactionsInsoluble in water.
  • Reactivity ProfileSulfanilic acid is an amino acid. Reacts weakly with both acids and bases.
  • Fire HazardFlash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.
  • Chemical SynthesisSulfanilic acid can be produced by sulfonation of aniline.
  • Purification MethodsCrystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]
Sulfanilic acid Preparation Products And Raw materials
Sulfanilic acid(121-57-3)Related Product Information
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  • Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
  • Tel:400-620-6333 021-20337333-801
  • Company Name:Wuhan Xinyangruihe Chemical Technology Co., Ltd. Gold
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  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801