Saccharine

Saccharin is commonly used as a sugar substitute because it doesn’t contain calories or carbs. Humans can’t break down saccharin, so it leaves your body unchanged. It’s around 300–400 times sweeter than regular sugar, so you only need a small amount to get a sweet taste. In addition to carbonated diet drinks, saccharin is used to sweeten low-calorie candies, jams, jellies, and cookies. It’s also used in many medicines.

The FDA limits the acceptable amount to less than 12 milligrams (mg) per fluid ounce. In processed foods, saccharin cannot exceed 30 mg per serving size.