Chemical Properties
Light yellow to brown crystalline powder
Uses
5-Amino-2-chloropyridine was used in the synthesis of [
2H
5]2-amino-l-methyl-6-phenylimidazo[4,5-
b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.
Definition
ChEBI: 3-Amino-6-chloropyridine is an aminopyridine.
General Description
5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine.
