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Tris(hydroxymethyl)aminomethane Structure

Tris(hydroxymethyl)aminomethane

Chemical Properties

Melting point 167-172 °C(lit.)
Boiling point 219-220 °C10 mm Hg(lit.)
Density  1,353 g/cm3
vapor pressure  0.0267 hPa (20 °C)
refractive index  1.4170 (estimate)
Flash point 219-220°C/10mm
storage temp.  20-25°C
solubility  H2O: 4 M at 20 °C, clear, colorless
form  crystalline
color  white
PH Range 7 - 9
PH 10.5-12.0(4 m in water, 25 °C)
pka 8.1(at 25℃)
Water Solubility  550 g/L (25 ºC)
λmax λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08
Sensitive  Hygroscopic
Merck  14,9772
BRN  741883
Stability Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
InChIKey LENZDBCJOHFCAS-UHFFFAOYSA-N
CAS DataBase Reference 77-86-1(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII 023C2WHX2V
ATC code B05BB03,B05XX02
NIST Chemistry Reference 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System Tris(hydroxymethyl)aminomethane (77-86-1)

Safety

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39-24/25-23
WGK Germany  2
RTECS  TY2900000
3
TSCA  Yes
HazardClass  IRRITANT
HS Code  29221980
Hazardous Substances Data 77-86-1(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rat > 5000 mg/kg
NFPA 704:
1
2 1

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