Description References
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6-Aminocaproic acid

Description References
6-Aminocaproic acid Structure
6-Aminocaproic acid
  • CAS No.60-32-2
  • Chemical Name:6-Aminocaproic acid
  • Synonyms:ACS;EACS;EACA;177jd;cy116;Hepin;Amicar;Amikar;CY 116;177 J.D
  • CBNumber:CB5223888
  • Molecular Formula:C6H13NO2
  • Formula Weight:131.17
  • MOL File:60-32-2.mol
6-Aminocaproic acid Property
  • Melting point: :207-209 °C (dec.)(lit.)
  • Boiling point: :242.49°C (rough estimate)
  • Density  :1.03 g/mL at 20 °C
  • vapor pressure  :<0.1 hPa (20 °C)
  • refractive index  :1.4870 (estimate)
  • Flash point: :207-209°C
  • storage temp.  :2-8°C
  • solubility  :H2O: 50 mg/mL
  • form  :powder
  • pka :4.373(at 25℃)
  • color  :white
  • PH :7.0-7.5 (50g/l, H2O, 20℃)
  • Water Solubility  :SOLUBLE
  • Merck  :14,432
  • BRN  :906872
  • InChIKey :SLXKOJJOQWFEFD-UHFFFAOYSA-N
  • CAS DataBase Reference :60-32-2(CAS DataBase Reference)
  • NIST Chemistry Reference :Hexanoic acid, 6-amino-(60-32-2)
  • EPA Substance Registry System :Hexanoic acid, 6-amino-(60-32-2)
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • WGK Germany  :2
  • RTECS  :MO6300000
  • TSCA  :Yes
  • HS Code  :29224995
  • Hazardous Substances Data :60-32-2(Hazardous Substances Data)
  • Toxicity :LD50 in rats (g/kg): 7.0 i.p.; ~3.3 i.v. (Hallesy)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements
  • H315:Causes skin irritation
  • H319:Causes serious eye irritation
  • H320:Causes eye irritation
  • H335:May cause respiratory irritation
  • Precautionary statements
  • P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264:Wash hands thoroughly after handling.
  • P264:Wash skin thouroughly after handling.
  • P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
  • P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
  • P405:Store locked up.
6-Aminocaproic acid Price More Price(28)
  • Brand: Sigma-Aldrich
  • Product number: 07260
  • Product name : 6-Aminohexanoic acid
  • Purity: ≥98.5% (NT)
  • Packaging: 100g
  • Price: $103
  • Updated: 2018/11/13
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  • Brand: Sigma-Aldrich
  • Product number: 07260
  • Product name : 6-Aminohexanoic acid
  • Purity: ≥98.5% (NT)
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  • Brand: TCI Chemical
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  • Product name : 6-Aminohexanoic Acid
  • Purity: >98.0%(T)
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  • Updated: 2018/11/22
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  • Brand: TCI Chemical
  • Product number: A0312
  • Product name : 6-Aminohexanoic Acid
  • Purity: >98.0%(T)
  • Packaging: 500g
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  • Updated: 2018/11/22
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  • Brand: Alfa Aesar
  • Product number: A14719
  • Product name : 6-Aminohexanoic acid, 99%
  • Purity: 
  • Packaging: 100g
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  • Updated: 2018/11/13
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6-Aminocaproic acid Chemical Properties,Usage,Production

  • Description 6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
  • References https://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
    https://en.wikipedia.org/wiki/Aminocaproic_acid
  • Chemical Properties white crystalline powder
  • Uses hemostatic
  • Uses 6-Aminohexanoic Acid is a reagent commonly used for the extraction of aldehydes from reaction mixtures. 6-Aminohexanoic Acid has also been shown to improve solubilization of membrane proteins in elect rophoresis. Studies suggest that 6-Aminohexanoic Acid inhibits the activation of the first component of the complement system.
  • Uses Propylparaben Food preservative
  • Uses EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
  • Definition ChEBI: An amino-acid anion that is the conjugate base of 6-aminohexanoic acid.
  • brand name Amicar (Xanodyne).
  • Safety Profile Moderately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.
  • Veterinary Drugs and Treatments Aminocaproic acid has been used as a treatment to degenerative myelopathy (seen primarily in German shepherds), but no controlled studies documenting its efficacy were located. There is interest in evaluating aminocaproic acid for adjunctive treatment of thrombocytopenia in dogs, but efficacy and safety for this purpose remains to be investigated. In humans, it is primarily used for treating hyperfibrinolysis-induced hemorrhage.
6-Aminocaproic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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