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60-32-2

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Identification

Name
6-Aminocaproic acid
CAS
60-32-2
Synonyms
6-AMINOCAPROIC ACID
6-AMINOHEXANOIC ACID
6-AMINO-N-CAPROIC ACID
6-AMINO-N-HEXANOIC ACID
6-L-AMINOHEXANOIC ACID
AMINOCAPROIC ACID
EACA
EPSILON-AMINOCAPROIC ACID
EPSILON-AMINO HEXANOIC ACID
EPSILON-AMINO-N-CAPROIC ACID
H-6-AHX-OH
H-ACP(6)-OH
H-ACP-OH
H-AHX(6)-OH
H-E-ACP-OH
H-EPSILON-ACP-OH
H-EPSILON-AHX-OH
H-EPSILON-AMINOCAPROIC ACID
NH2-(CH2)5-COOH
OMEGA-AMINOCAPROIC ACID
EINECS(EC#)
200-469-3
Molecular Formula
C6H13NO2
MDL Number
MFCD00008238
Molecular Weight
131.17
MOL File
60-32-2.mol

Chemical Properties

Appearance
white crystalline powder
mp 
207-209 °C (dec.)(lit.)

density 
1.03 g/mL at 20 °C

Fp 
207-209°C
storage temp. 
2-8°C

solubility 
H2O: 50 mg/mL

form 
powder

color 
white

Water Solubility 
SOLUBLE
Detection Methods
T,NMR
Merck 
14,432
BRN 
906872
CAS DataBase Reference
60-32-2(CAS DataBase Reference)
NIST Chemistry Reference
Hexanoic acid, 6-amino-(60-32-2)
EPA Substance Registry System
60-32-2(EPA Substance)

Safety Data

Hazard Codes 
Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
WGK Germany 
2

RTECS 
MO6300000

HS Code 
29224995
Safety Profile
Moderately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.
Hazardous Substances Data
60-32-2(Hazardous Substances Data)

Raw materials And Preparation Products

Material Safety Data Sheet(MSDS)

Questions And Answer

Description
6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
References
https://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
https://en.wikipedia.org/wiki/Aminocaproic_acid

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