Heptan-4-on

Bezeichnung:Heptan-4-on

CAS-Nr123-19-3

Englisch Name:4-Heptanone

CBNumberCB4487971

SummenformelC7H14O

Molgewicht114.19

MOL-Datei123-19-3.mol

Synonyma

Heptan-4-on

Butyron

4-Heptanon

Heptan-4-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	-33 °C (lit.)
Siedepunkt	145 °C (lit.)
Dichte	0.817 g/mL at 25 °C (lit.)
Dampfdichte	3.94 (vs air)
Dampfdruck	5.2 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.408(lit.)
FEMA	2546 \| 4-HEPTANONE
Flammpunkt	120 °F
storage temp.	Store below +30°C.
Löslichkeit	H2O: insoluble
Aggregatzustand	Liquid
Farbe	Clear colorless to light yellow
Geruch (Odor)	at 10.00 % in dipropylene glycol. fruity cheese sweet cognac pineapple
Geruchsart	fruity
Explosionsgrenze	1%(V)
Wasserlöslichkeit	4.6 g/L (20 ºC)
Merck	14,3345
JECFA Number	287
BRN	1699049
Expositionsgrenzwerte	TLV-TWA 235 mg/m³ (50 ppm) (NIOSH).
Dielectric constant	12.6（17℃）
Stabilität	Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, strong reducing agents.
InChIKey	HCFAJYNVAYBARA-UHFFFAOYSA-N
LogP	1.97
CAS Datenbank	123-19-3(CAS DataBase Reference)
NIST chemische Informationen	4-Heptanone(123-19-3)
EPA chemische Informationen	4-Heptanone (123-19-3)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	10-20/22-20-R20-R10-2017/10/20
S-Sätze:	24/25-S24/25
RIDADR	UN 2710 3/PG 3
OEB	A
OEL	TWA: 50 ppm (235 mg/m3)
WGK Germany	2
RTECS-Nr.	MJ5600000
Selbstentzündungstemperatur	430 °C
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29141900
Giftige Stoffe Daten	123-19-3(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 3021 mg/kg LD50 dermal Rabbit 4585 mg/kg

Gefahreninformationscode (GHS)

4-Heptanone Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Reagiert mit Oxidationsmitteln, Basenund Reduktionsmitteln.
ARBEITSPLATZGRENZWERTE
TLV: 50 ppm (als TWA); (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt langsam eine gesundheitsschädliche Kontamination der Luft ein; viel schneller jedoch beim Versprühen oder Dispergieren.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt leicht die Augen und die Haut. Der Dampf reizt die Atemwege. Exposition gegenüber hohen Konzentrationen kann zu Bewusstseinstrübung führen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Die Flüssigkeit entfettet die Haut.
LECKAGE
Zündquellen entfernen. Belüftung. Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R20:Gesundheitsschädlich beim Einatmen.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
4-Heptanone has a penetrating odor and burning taste. It is prepared by passing butyric acid over a wood coal at 425°C and then over cerium oxide at 500°C or over thorium oxide; also over manganese oxide at 400 - 425°C.
Chemische Eigenschaften
4-Heptanone has a penetrating odor and burning taste.
Chemische Eigenschaften
4-Heptanone is a colourless liquid. Sp.Gr. 0.82. B.P. 144℃. 0.5% soluble in water, miscible with alcohol and oils. Powerful and diffusive ethereal-fruity, pungent odor, in dilution reminiscent of Pineapple-Strawberry. Fruity, Strawberry type flavor, but not really sweet, and lacks naturalness.
Occurrence
Reported found in apple juice, papaya, pear, cabbage, baked potato, roasted peanut, chicken fat, coffee, bachang (Mangifera foetida L ) and rooibus tea (Aspalathius linearis)
Verwenden
4-Heptanone is used as a solvent for nitrocellulose as well as in organic synthesis. It is involved in the preparation of flavorings. It is used as an intermediate in the synthesis of active pharmaceutical ingredients. Further, it is used in paints and coatings.
Verwenden
Solvent for nitrocellulose, oils, resins, and polymers and in flavorings
Verwenden
Dipropyl ketone (DPK) is used as a solventin oils, resins, nitrocellulose, and polymers;and as a flavoring compound.
synthetische
By passing butyric acid over wood coal at 425°C and then over cerium oxide at 500°C or over thorium oxide; also over manganese oxide at 400 to 425°C.
Definition
ChEBI: 4-heptanone is a dialkyl ketone that is heptane in which the two methylene protons at position 4 have been replaced by an oxo group. It has a role as a biomarker, a human xenobiotic metabolite, a human urinary metabolite and a rat metabolite. It derives from a hydride of a heptane.
Aroma threshold values
Detection: 8.2 to 41 ppb; aroma characteristics at 1.0%: sweet ethereal, banana fruity, pungent, green apple with cheese nuances.
Taste threshold values
Taste characteristics at 5 ppm: fruity, banana, green apple, blue cheese with nut-like nuances.
Synthesis Reference(s)
The Journal of Organic Chemistry, 59, p. 245, 1994 DOI: 10.1021/jo00080a042
Allgemeine Beschreibung
A colorless liquid with a pleasant odor. Insoluble in water and less dense than water. Flash point 120°F. Toxic by inhalation. A skin irritant. Used to make flavorings and as a solvent.
Air & Water Reaktionen
Flammable. Insoluble in water.
Reaktivität anzeigen
4-Heptanone is incompatible with the following: Oxidizers .
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Health Hazard
Inhalation of DPK vapors can cause narcosisand irritation of the eyes and respiratory tract.Exposure to 4000 ppm for 4 hours was fatalto rats. This compound exhibited low to verylow oral toxicity in test animals.
LD50 value, oral (rats): 3730 mg/kg.
Brandgefahr
Combustible liquid; flash point (closed cup) 49°C (120°F); vapor density 3.9 (air = 1); vapor pressure 5.2 torr at 20°C (68°F); fireextinguishing agent: “alcohol” foam or water spray. DPK forms explosive mixtures with air; LEL and UEL values have not been reported. It is incompatible with strong acids, alkalies, and oxidizers. .
Biochem/physiol Actions
Taste at 5 ppm
Sicherheitsprofil
and skin contact. A skin and eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use CO2, dry chemical, alcohol foam, fog, and mist. When heated to decomposition it emitsacrid smoke and fumes. See also KETONES.
mögliche Exposition
High or repeated exposures maydamage the liver and kidney. Repeated contact can dry outthe skin, causing irritation and rash.
Stoffwechsel
When 950 mg methyl amyl ketone/kg body weight was administered orally to rabbits, 40% was excreted as heptyl-2-glucuronide, and traces of the unchanged ketone were also found in the urine (Kamil, Smith & Williams, 1953). 2-Heptanone (methyl amyl ketone) was identified as being among the approximately 300 compounds present in the volatile constituents of urine from male and female subjects (Zlatkis & Liebich, 1971).
Lager
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with dipropyl ketone you should be trainedon its proper handling and storage. Store in tightly closedcontainers in a cool, well-ventilated area away from oxidizers. Metal containers involving the transfer of this chemical should be grounded and bonded. Where possible,automatically pump liquid from drums or other storage containers to process containers. Drums must be equipped withself-closing valves, pressure vacuum bungs, and flamearresters. Use only nonsparking tools and equipment, especially when opening and closing containers of this chemical. Sources of ignition, such as smoking and open flames,are prohibited where this chemical is used, handled, orstored in a manner that could create a potential fire orexplosion hazard. Wherever this chemical is used, handled,manufactured, or stored, use explosion-proof electricalequipment and fittings
Versand/Shipping
This compound requires a shipping label of“FLAMMABLE LIQUID.” It falls in Hazard Class 3 andPacking Group II.
läuterung methode
Dry 4-pentanone with CaSO4, then distil it from P2O5 under nitrogen. [Beilstein 1 IV 3323.]
Inkompatibilitäten
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, getmedical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Waste disposal
DPK is burned in a chemical incineratorequipped with an afterburner and scrubber.

4-Heptanone Upstream-Materialien And Downstream Produkte

Heptan-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

123-19-3, 4-Heptanone Verwandte Suche:

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