Калия цитрат

Описание

Potassium citrate is a potassium salt of citric acid with the molecular formula C₆H₅K₃O₇. It is a white, slightly hygroscopic crystalline powder. It is odorless with a saline taste.
As a food additive, potassium citrate is used to regulate acidity and is known as E number E332. Medicinally, it may be used to control kidney stones derived from either uric acid or cystine.

Химические свойства

Colorless or white crystals or powder; cooling, saline taste; odorless; deliquescent. Soluble in water and glycerol; almost insoluble in alcohol.

Использование

potassium citrate is it acts as a buffer, maintaining product pH constant, a pH adjuster and a product stabilizer. This is a potassium salt.

Определение

ChEBI: The anhydrous form of the tripotassium salt of citric acid.

Методы производства

Potassium citrate is produced by adding potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases, filtering the solution and evaporating to granulation.

Промышленное использование

Potassium citrate is used in the United Kingdom as an over-the-counter drug for the relief from discomfort experienced in mild urinary-tract infections by increasing the urinary pH. It should be not given to men if they experience pain in the kidney area (risk of kidney stones) or if blood or pus is present in the urine. Also, patients with raised blood pressure or diabetes should avoid taking potassium citrate without consultation with their general practitioner (GP). Caution is generally advised to patients with renal impairment, cardiac problems and the elderly [3a].

Профиль безопасности

Poison by intravenous route. When heated to decomposition it emits toxic fumes of K2O.

Меры предосторожности

Potassium citrate is usually administered by mouth in dilute aqueous solution. This is because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards.
In states where non-prescription potassium citrate is legal, the maximum allowable over-the-counter (OTC) dose for elemental potassium is regulated by the FDA to be no more than 100 mg (approximately 3 % of the daily allowance ) . Pure potassium citrate contains 38.28 % potassium.