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Dimethylamine hydrochloride

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Dimethylamine hydrochloride Basic information
Dimethylamine hydrochloride Chemical Properties
  • Melting point:170-173 °C(lit.)
  • Boiling point:95.79°C (rough estimate)
  • Density 0.8949 (rough estimate)
  • vapor pressure <0.1 hPa (25 °C)
  • refractive index 1.4202 (estimate)
  • storage temp. Store below +30°C.
  • solubility H2O: soluble0.5g/10 mL
  • form Crystalline Powder or Crystals
  • color White to off-white
  • PH5 (100g/l, H2O, 20℃)
  • Water Solubility 3000 g/L (20 ºC)
  • Sensitive Hygroscopic
  • Merck 14,3228
  • BRN 3589311
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • CAS DataBase Reference506-59-2(CAS DataBase Reference)
  • EPA Substance Registry SystemMethanamine, N-methyl-, hydrochloride (506-59-2)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22-36/37/38
  • Safety Statements 26-36/37-37/39-36
  • WGK Germany 1
  • RTECS IQ0220000
  • 3-9
  • TSCA Yes
  • HS Code 29211190
  • ToxicityLD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
Dimethylamine hydrochloride Usage And Synthesis
  • Chemical Propertieswhite crystals
  • UsesDimethylamine hydrochloride is a precursor to several industrially significant compounds.
  • UsesAs accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.
  • ApplicationDimethylamine hydrochloride is a raw material for organic synthesis. It is also used as a catalyst and magnesium reagent for acetylation analysis.
    Dimethylamine hydrochloride has been used in the preparation of hexamethylmelamine-methyl-14C. It has also been used to prepare the standard solution of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) while determing methylamines and trimethylamine-N-oxide in particulate matter. Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.
  • Purification MethodsCrystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.]
Dimethylamine hydrochloride Preparation Products And Raw materials
Dimethylamine hydrochloride(506-59-2)Related Product Information
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