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Cinchonidine

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Cinchonidine Basic information
Cinchonidine Chemical Properties
  • Melting point:204-206 °C(lit.)
  • alpha -115 º (c=1, EtOH)
  • Boiling point:436.16°C (rough estimate)
  • Density 1.0863 (rough estimate)
  • refractive index -107.5 ° (C=1, EtOH)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility 0.25g/l
  • form Crystalline Powder
  • pka5.80, 10.03(at 25℃)
  • color White to cream
  • PH9 (0.2g/l, H2O, 20℃)
  • optical activity[α]23/D 109.2°, c = 1.5 in ethanol
  • Water Solubility Insoluble
  • Sensitive Light Sensitive
  • Merck 14,2286
  • BRN 89690
  • Stability:Stable, but light-sensitive. Incompatible with strong oxidizing agents.
  • InChIKeyKMPWYEUPVWOPIM-NAHPKXJFSA-N
  • CAS DataBase Reference485-71-2(CAS DataBase Reference)
  • NIST Chemistry ReferenceCinchonidine(485-71-2)
  • EPA Substance Registry SystemCinchonan-9-ol, (8.alpha.,9R)- (485-71-2)
Safety Information
MSDS
Cinchonidine Usage And Synthesis
  • Chemical Propertieswhite to light yellow crystal powde
  • Usesantiamebic, antiprotozoal
  • UsesOccurs in most varieties of Cinchona
  • DefinitionChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.
  • Purification MethodsCrystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.]
Cinchonidine Preparation Products And Raw materials
Cinchonidine(485-71-2)Related Product Information
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