1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
1-Methylpiperazine is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP)
ChEBI: 1-Methylpiperazine is a N-methylpiperazine.
Flammability and Explosibility
Flammable
Poison by
intraperitoneal route. Moderately toxic by
inhalation, ingestion, and skin contact. A
severe skin and eye irritant. Flammable
liquid when exposed to heat or flame; can
react with oxidizing materials. To fight fire,
use alcohol foam, CO2, dry chemical. When
heated to decomposition it emits toxic
fumes of NOx.
