Dibasic Sodium Phosphate

Dibasic Sodium Phosphate is used as a sequestrant, emulsifier, and buffer in foods; as a mordant in dyeing for weighting silk, in tanning, in manufacturing of enamels, ceramics, detergents, boiler compounds; as fireproofing agent in soldering and brazing instead of borax; as reagent and buffer in analytical chemistry, cathartic., laxative. It is a very high buffering capacity reagent and is widely used in molecular biology, biochemistry, and chromatography. Useful in conjunction with Sodium Phosphate and monobasic in preparing biological buffers. Used in many applications, including the purification of antibodies.

Dibasic sodium phosphate is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4

Dibasic Sodium Phosphate can affect humans when breathed in and by passing through your skin. Contact can irritate the skin and eyes. Breathing this compound can irritate the nose and throat, causing coughing and wheezing. High and repeated exposure can cause a skin rash (dermatitis).