2-Chlor-2'-ethyl-N-(2-methoxy-1-methylethyl)-6'-methylacetanilid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H317：Kann allergische Hautreaktionen verursachen.

• Sicherheit

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Metolachlor Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  GERUCHLOSE KLARE FLüSSIGKEIT.

• ARBEITSPLATZGRENZWERTE

  TLV nicht festgelegt (ACGIH 2005).
  MAK nicht festgelegt (DFG 2005).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Inhalation des Aerosols.

• INHALATIONSGEFAHREN

  Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Versprühen schnell erreicht werden.

• LECKAGE

  NICHT in die Umwelt gelangen lassen. Ausgelaufene Flüssigkeit in abgedeckten Behältern sammeln. An sicheren Ort bringen. Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel.

• R-Sätze Betriebsanweisung:

  R43:Sensibilisierung durch Hautkontakt möglich.
  R36:Reizt die Augen.
  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
  R11:Leichtentzündlich.

• S-Sätze Betriebsanweisung:

  S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S16:Von Zündquellen fernhalten - Nicht rauchen.

• Beschreibung

  Metolachlor is a colorless or tan to brown,oily liquid with a slightly sweet odor. Molecularweight 5 283.83; Boiling point = 100℃ at 0.001 mmHg. Itis stable to about 300℃. Hazard Identification (based onNFPA-704 M Rating System): Health 1, Flammability 0,Reactivity 0. Slightly soluble in water.

• Chemische Eigenschaften

  Pale Yellow Oil

• Chemische Eigenschaften

  Metolachlor is a colorless or tan to brown, oily liquid. Slightly sweet odor.

• Verwenden

  Preemergence herbicide used to control most annual grasses and many annual weeds in beans, chickpeas, corn, cotton, milo, okra, peanuts, peas, potatoes, safflower, soybeans and some ornamentals.

• Verwenden

  A selective pre-emergence herbicide.

• Definition

  ChEBI: 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide is an organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl) group at the nitrogen atom. It is an aromatic amide, an ether, a member of benzenes and an organochlorine compound.

• Vorbereitung Methode

  The industrial production of metolachlor begins with the acylation of 2-ethyl-6-methylaniline using chloroacetyl chloride to form a key intermediate. This is followed by alkylation with 1-methoxypropan-2-ol, introducing the side chain that enhances herbicidal activity. The most advanced commercial process involves a highly efficient enantioselective catalytic hydrogenation step to produce S-metolachlor, the biologically active isomer, using chiral ferrocenyl ligands and transition metal catalysts. This process achieves high selectivity and conversion rates, reducing reaction time and improving environmental performance compared to older methods.

• Allgemeine Beschreibung

  Tan to brown oily liquid with a slightly sweet odor. Slightly soluble in water and denser than water. Hence sinks in water. Soluble in most organic solvents. Used as a selective herbicide.

• Air & Water Reaktionen

  Slightly soluble in water. Hydrolyzed by strong mineral acids and strong alkalis.

• Reaktivität anzeigen

  Metolachlor is a chlorinated acetamide. May react with azo and diazo compounds to generate toxic gases. May form flammable gases with strong reducing agents. Combustion generates mixed oxides of nitrogen (NOx).

• Health Hazard

  Can cause skin irritation and eye irritation. Headache and nausea may occur following prolong exposure.

• Landwirtschaftliche Anwendung

  Herbicide: Not approved for use in EU countries. Registered for use in the U.S. Metolachlor is a selective herbicide that is usually applied to crops before plants emerge from the soil, and is used to control certain broadleaf and annual grassy weeds in field corn, soybeans, peanuts, grain sorghum, potatoes, pod crops, cotton, safflower, stone fruits, nut trees, highway rights-of-way and woody ornamentals. Prior to the RED of April, 1995, its primary use was on corn, soybeans and sorghum. It inhibits protein synthesis; thus, high-protein crops (e. g., soy) can be adversely affected by excessive metolachlor application. Additives may be included in product formulations to help protect sensitive crops (i.e., sorghum) from injury.

• Handelsname

  BICEP®[C]; BROADSTRIKE®; CGA- 24705®; CINCH®; CODAL®; COTORAN® MULTI®; CYCLE®[C] DREXEL ME-TOO-LACHLOR®; DUAL®; DUAL MAGNUM®; DUET®[C]; INTER PLUS®; MEDAL®[C]; MILOCEP®; ONTRACK 8E®[C]; PENNANT®[C]; PRELUDE®[C]; PRIMAGRAM®; PRIMEXTRA®; TURBO®

• Mechanism of action

  Selective, reduces seed germination. Inhibition of very long chain fatty acids (VLCFA, inhibition of cell division)

• mögliche Exposition

  Metolachlor is a chlorinated acetamide selective herbicide used for weed control in corn and for controlling grasses in a variety of crops including cotton and peanuts.

• Erste Hilfe

  If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobin in urine.

• Environmental Fate

  Soil. Metolachlor and its degradation products combine with humic acids in soils and small quantities are degraded to carbon dioxide (Ashton and Monaco, 1991). In soil, the fungus Chaetomium globosum degraded metolachlor to 2-chloro-N-(2-ethyl-6-methylphenyl) acetamide, 2-hydroxy-N-(2-methylvinylphenyl)-N-(methoxyprop-2-yl)acetamide, 3- hydroxy-8-methyl-N-(methoxyprop-2-yl)-2-oxo-1,2,3,4-tetrahydraquinoline, 2-chloro-N- (2-ethyl-6-methylphenyl)-N-(hydroxyprop-2-yl)acetamide and the tentatively identified compounds 3-hydroxy-1-isopropyl-8-methyl-2-oxo-1,2,3,4-tetrahydroquinoline, N-(methoxyprop- 2-yl)-8-methyl-2-oxo-1,2,3,4-tetrahydroquinoline, N-(methoxyprop-2-yl)-N-(2- methyl-6-vinyl)aniline and 1-(methoxyprop-2-yl)-7-methyl-2,3-dihydroindole (McGahen 8). Metolachlor was transformed by a strain of soil actinomycetes to the following products: 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(hydroxyprop-2-yl)acetamide, 2-chloro-N- 2-(1-hydroxyethyl)-6-(methylphenyl)-N-(hydroxyprop-2-yl)acetamide, 2-chloro-N-(2- ethyl-6-hydroxymethylphenyl)-N-(hydroxy-prop-2-yl)-acetamide, diastereoisomers of 2- chloro-N-(2-ethyl-6-hydroxymethylphenyl)-N-(methoxyprop-2-yl)acetamide and 2- chloro-N-2-(hydroxyethyl)-6-hydroxymethylphenyl)-N-(methoxyprop-2-yl)acetamide. These products were formed via hydroxylation of both the N-alkyl and alkyl side chains (Krause et al., 1985). In sterilized soil, metolachlor did not degrade after 4 months (Bouchard et al., 1982).
  Zimdahl and Clark (1982) reported half-lives of 15–38 and 33–100 days for the herbicide in clay loam soil and sandy loam soil, respectively. They also reported that soil moisture increased the dissipation rate. At 20°C, the dissipation rates of metolachlor in the clay loam and sandy loam soils at 20, 50 and 80% soil moisture contents were 0.028, 0.053, 0.062 and 0.016, 0.028 and 0.037/day, respectively. The half-lives of metolachlor in soil at maintained at temperatures of 30 and 40°C were approximately 3.85 and 2.75 weeks, respectively (Bravermann et al., 1986). The reported half-lives of metolachlor in soil is approximately 6 days (Worthing and Hance, 1991) and 3–4 weeks (Bowman, 1988). Groundwater. According to the U.S. EPA (1986) metolachlor has a high potential to leach to groundwater.
  Plant. Metabolizes in plants forming water soluble, polar, nonvolatile products (Hartley and Kidd, 1987) and glutathione conjugates (Breaux et al., 1987).
  Chemical/Physical. The volatilization half-life of metolachlor in an unstirred solution was 20 days at 40°C. Volatilization is not significant at temperatures < 25°C (Lau et al., 1995).

• Stoffwechselwegen

  A stable bacterial community absorbs and transforms metolachlor from a liquid medium. From the medium of the 7 day-old culture of the bacterial community, 2- hydroxy-N-(2-methyl-6-vinylphenyl)-N-(2-methoxy- methylethyl)acetamide and 4-(2-ethyl-6-methylphenyl)- 5-methyl-3-morpholinone are identified. The products recovered from cells of J4-A include dechlorinated metolachlor, a thiol compound, a more complicated conjugate, and a non-sulfur-containing conjugate. By sorghum microsomes, O-demethylation occurs in the metolachlor degradation process.

• Lager

  Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers. Where possible, automatically pump liquid from drums or other storage containers to process containers

• Versand/Shipping

  UN2902 Pesticides, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

• Inkompatibilitäten

  Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrates. Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur).

• Waste disposal

  In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

• Pestizidtyp

  Herbicide

Metolachlor Upstream-Materialien And Downstream Produkte

2-Chlor-2'-ethyl-N-(2-methoxy-1-methylethyl)-6'-methylacetanilid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(243)Suppliers

51218-45-2, Metolachlor Verwandte Suche: