Ethyl-4-hydroxybenzoat Produkt Beschreibung

Ethylparaben Struktur
120-47-8
  • CAS-Nr.120-47-8
  • Bezeichnung:Ethyl-4-hydroxybenzoat
  • Englisch Name:Ethylparaben
  • Synonyma:Ethyl-4-hydroxybenzoat
    Ethyl;Sobrol A;nipazina;solbrola;Of ethyl;Solbro A;Easeptol;Keloform;Mycocten;napagina
  • CBNumber:CB5119772
  • Summenformel:C9H10O3
  • Molgewicht:166.17
  • MOL-Datei:120-47-8.mol
Ethyl-4-hydroxybenzoat physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :114-117 °C(lit.)
  • Siedepunkt: :297-298 °C(lit.)
  • Dichte :1.1708 (rough estimate)
  • Dampfdruck :0.00012 hPa (25 °C)
  • Brechungsindex :1.5286 (estimate)
  • Flammpunkt: :297-298°C
  • storage temp.  : 0-6°C
  • Löslichkeit :Very slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
  • Aggregatzustand :Crystalline Powder
  • Farbe :White
  • PH :4.5-5.5 (H2O, 20°C) (saturated solution)
  • Wasserlöslichkeit :Slightly soluble in water.
  • Merck  :14,3837
  • BRN  :1101972
  • Stabilität: :Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
  • CAS Datenbank :120-47-8(CAS DataBase Reference)
  • NIST chemische Informationen :Ethylparaben(120-47-8)
  • EPA chemische Informationen :Benzoic acid, 4-hydroxy-, ethyl ester(120-47-8)
Sicherheit
  • Kennzeichnung gefährlicher :Xi
  • R-Sätze: :36/37/38
  • S-Sätze: :26-36-24/25
  • WGK Germany  :1
  • RTECS-Nr. :DH2190000
  • Selbstentzündungstemperatur :495 °C
  • TSCA  :Yes
  • HS Code  :29182930
  • Giftige Stoffe Daten :120-47-8(Hazardous Substances Data)
  • Toxizität :LD50 orally in Rabbit: > 2000 mg/kg

Ethylparaben Chemische Eigenschaften,Einsatz,Produktion Methoden

  • R-Sätze Betriebsanweisung: R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  • S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
    S24/25:Berührung mit den Augen und der Haut vermeiden.
  • Chemische Eigenschaften white crystalline powder
  • Chemische Eigenschaften Ethylparaben occurs as a white, odorless or almost odorless, crystalline powder.
  • Verwenden An antimicrobial
  • Verwenden bronchodilator, tocolytic
  • Verwenden Preservative for pharmaceuticals.
  • Vorbereitung Methode Ethylparaben is prepared by the esterification of p-hydroxybenzoic acid with ethanol (95%).
  • Pharmazeutische Anwendungen Ethylparaben is widely used as an antimicrobial preservative in cosmetics,food products, and pharmaceutical formulations.
    It may be used either alone or in combination with other paraben esters or with other antimicrobial agents. In cosmetics it is one of the most frequently used preservatives.
    The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
    Owing to the poor solubility of the parabens, paraben salts, particularly the sodium salt, are frequently used. However, this may cause the pH of poorly buffered formulations to become more alkaline.
  • Kontakt-Allergie This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
  • Sicherheit(Safety) Ethylparaben and other parabens are widely used as antimicrobial preservatives in cosmetics, food products, and oral and topical pharmaceutical formulations.
    Systemically, no adverse reactions to parabens have been reported, although they have been associated with hypersensitivity reactions. Parabens, in vivo, have also been reported to exhibit estrogenic responses in fish.(10) The WHO has set an estimated total acceptable daily intake for methyl-, ethyl-, and propylparabens at up to 10 mg/kg body-weight.
    LD50 (mouse, IP): 0.52 g/kg
    LD50 (mouse, oral): 3.0 g/kg
  • Lager Aqueous ethylparaben solutions at pH 3–6 can be sterilized by autoclaving, without decomposition. At pH 3–6, aqueous solutions are stable (less than 10% decomposition) for up to about 4 years at room temperature, while solutions at pH 8 or above are subject to rapid hydrolysis (10% or more after about 60 days at room temperature).
    Ethylparaben should be stored in a well-closed container in a cool, dry place.
  • Inkompatibilitäten The antimicrobial properties of ethylparaben are considerably reduced in the presence of nonionic surfactants as a result of micellization. Absorption of ethylparaben by plastics has not been reported, although it appears probable given the behavior of other parabens. Ethylparaben is coabsorbed on silica in the presence of ethoxylated phenols. Yellow iron oxide, ultramarine blue, and aluminum silicate extensively absorb ethylparaben in simple aqueous systems, thus reducing preservative efficacy.
    Ethylparaben is discolored in the presence of iron and is subject to hydrolysis by weak alkalis and strong acids.
  • Regulatory Status Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral, otic, and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Ethylparaben Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ethyl-4-hydroxybenzoat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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120-47-8, Ethylparaben Verwandte Suche:
  • 4-Carbethoxyphenol
  • nipaginaa
  • Nipazin A
  • nipazina
  • Para-hydroxybenzoic acid ethyl ester
  • p-Carbethoxyphenol
  • p-Hydroxybenzoic ethyl ester
  • p-hydroxy-benzoicaciethylester
  • p-hydroxybenzoicethylester
  • p-Oxybenzoesaeureaethylester
  • Sobrol A
  • Solbrol A
  • solbrola
  • Tegosept E
  • ETHYLPARABEN,NF
  • 4-HYDROXYBENZOICACIDETHYLESTER(ETHYLPARABEN)
  • PARABEN,ETHYL
  • Ethyl-4-hydroxybenzoat
  • Ethyl P-Hdroxybenzoate
  • ETHYL 4-HYDROXYBENZOATE / ETHYLPARABEN
  • ETHYLP-HYDROXYBENZOATE/EASEPTOL
  • ETHYL-4-HYDROXYBENZOATE WITH HPLC
  • ETHYLPARABEN (ETHYL 4-HYDROXYBENZOATE)
  • 4-Hydroxybenzoic acid ethyl
  • Aceptin A
  • Sorbrol A
  • Ethyl 4-hydroxybenzoate,99%
  • Ethyl p-Hydrobenzoate
  • 2-Ethyl-4-hydroxy-benzoicacid
  • Ethyl-p-hydroxybenzoate 5g [120-47-8]
  • Ethylparaben (200 mg)
  • Of ethyl
  • Of ethyl (Ethylparaben)
  • Ethyl cheMosept
  • Solbro A
  • Ethyl 4-Hydroxybenzoate [for BiocheMical Research]
  • Ethyl Paraben (EP)
  • Ethyl p-Hydroxybenzoate (Ethylparaben)
  • Ethyl 4-Hydroxybenzoate,(S)
  • Ethyl 4-hydroxybenzoate, 99% 100GR
  • Mekkings E
  • NSC 23514
  • Ethylparaben 4-Hydroxybenzoic Acid Ethyl Ester
  • Easeptol
  • Ester etylowykwasu p-hydroksybenzoesowego
  • esteretylowykwasup-hydroksybenzoesowego
  • ethvlparaben
  • Ethyl
  • Ethyl para-hydroxybenzoate
  • Ethyl p-oxybenzoate
  • Ethylester kyseliny p-hydroxybenzoove
  • ethylesterkyselinyp-hydroxybenzoove
  • ethylhydroxybenzoate
  • 4-hydroxy-benzoicaciethylester
  • Aseptin a
  • Aseptine a
  • Aseptoform E
  • aseptoforme