5-Methyl-o-anisidin

Bezeichnung:5-Methyl-o-anisidin

CAS-Nr120-71-8

Englisch Name:2-Methoxy-5-methylaniline

CBNumberCB6191898

SummenformelC8H11NO

Molgewicht137.18

MOL-Datei120-71-8.mol

Synonyma

6-Methoxy-m-toluidin

5-Methyl-o-anisidin

2-Methoxy-5-methylanilin

5-Methyl-o-anisidin physikalisch-chemischer Eigenschaften

Schmelzpunkt	50-52 °C (lit.)
Siedepunkt	235 °C (lit.)
Dichte	1.0252 (rough estimate)
Dampfdichte	4.7 (vs air)
Dampfdruck	2.6Pa at 20℃
Brechungsindex	1.5647 (estimate)
Flammpunkt	>230 °F
storage temp.	Room Temperature, under inert atmosphere
Löslichkeit	Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
Aggregatzustand	Crystalline Chunks
pka	4.66±0.10(Predicted)
Farbe	Brown to black
Wasserlöslichkeit	Slightly soluble in hot water.
BRN	637071
Stabilität	Air Sensitive
InChIKey	WXWCDTXEKCVRRO-UHFFFAOYSA-N
LogP	1.65 at 23℃ and pH7
CAS Datenbank	120-71-8(CAS DataBase Reference)
IARC	2B (Vol. 27, Sup 7) 1987
NIST chemische Informationen	Benzenamine, 2-methoxy-5-methyl-(120-71-8)
EPA chemische Informationen	p-Cresidine (120-71-8)

Sicherheit

Kennzeichnung gefährlicher	T,Xi
R-Sätze:	45-22
S-Sätze:	53-45
WGK Germany	3
RTECS-Nr.	BZ6720000
F	9
HazardClass	IRRITANT
HS Code	29222990
Giftige Stoffe Daten	120-71-8(Hazardous Substances Data)
Toxizität	rat,LD50,oral,1450mg/kg (1450mg/kg),Huntingdon Research Center Reports. Vol. -, Pg. -, 1972.

Gefahreninformationscode (GHS)

2-Methoxy-5-methylaniline Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
WEISSE KRISTALLE.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen unter Bildung giftiger Rauche und reizender Rauche mit Stickstoffoxiden. Reagiert mit starken Oxidationsmitteln. Greift einige Kunststoff-, Gummi- und Beschichtungsarten an.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: Krebserzeugend Kategorie 2; (DFG 2004).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Möglicherweise krebserzeugend für den Menschen.
LECKAGE
Persönliche Schutzausrüstung: Atemschutzgerät, P3-Filter für giftige Partikel. Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen.
R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
p-Cresidine is a white crystalline solid.Molecular weight =137.20. Boiling point =235℃;Freezing/Melting point = 52℃; Flash point $ 112℃;Autoignition temperature =450℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 1, Reactivity 0. Practically insoluble in water.
Chemische Eigenschaften
brown to black crystalline chunks
Chemische Eigenschaften
p-Cresidine is a white crystalline solid.
Verwenden
p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.
Verwenden
2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.
Definition
ChEBI: Para-Cresidine is a member of methoxybenzenes.
Allgemeine Beschreibung
White to silver-gray odorless crystals.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
2-Methoxy-5-methylaniline is sensitive to moisture and temperatures greater than 104°F. Incompatible with strong oxidizing agents .
Hazard
A possible carcinogen.
Brandgefahr
2-Methoxy-5-methylaniline is nonflammable.
Sicherheitsprofil
Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Moderately toxic by ingestion. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
mögliche Exposition
p-Cresidine is used as an intermediate in the production of various azodyes, printing inks, and pigments; including 11 dyes that are produced commercially in the United States. Human exposure to p-Cresidine occurs primarily through inhalation of
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobinemia in urine.
Carcinogenicity
p-Cresidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Lager
Color Code—Blue (potential carcinogen): HealthHazard/Poison: Store in a secure poison location. Prior toworking with this chemical you should be trained on itsproper handling and storage. Before entering confined spacewhere this chemical may be present, check to make surethat an explosive concentration does not exist. Store intightly closed containers in a cool, well-ventilated areaaway from oxidizers. Store in a refrigerator under an inertatmosphere for prolonged storage. A regulated, marked areashould be established where this chemical is handled, used,or stored in compliance with OSHA Standard 1910.1045.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required
Inkompatibilitäten
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

2-Methoxy-5-methylaniline Upstream-Materialien And Downstream Produkte

5-Methyl-o-anisidin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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