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51-43-4

Name L(-)-Epinephrine
CAS 51-43-4
EINECS(EC#) 200-098-7
Molecular Formula C9H13NO3
MDL Number MFCD00002204
Molecular Weight 183.2
MOL File 51-43-4.mol

Chemical Properties

Appearance off-white powder
Melting point  215 °C (dec.)(lit.)
alpha  -51.5 º (c=4, 1M HCl, dry sub)
Boiling point  316.88°C (rough estimate)
density  1.1967 (rough estimate)
refractive index  -51.5 ° (C=4, 1mol/L HCl)
storage temp.  2-8°C
solubility  Practically insoluble in water, in ethanol (96 per cent) and in methylene chloride. It dissolves in hydrochloric acid.
form  Fine Crystalline Powder
pka 8.66(at 25℃)
color  White to light beige
Stability: Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive.
Water Solubility  <0.01 g/100 mL at 18 ºC
Decomposition  > 212°C
Sensitive  Air & Light Sensitive
Merck  14,3619
BRN  2368277
CAS DataBase Reference 51-43-4(CAS DataBase Reference)
NIST Chemistry Reference L-adrenaline(51-43-4)
EPA Substance Registry System 51-43-4(EPA Substance)

Safety Data

Hazard Codes  T
Risk Statements 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R36/37/38:Irritating to eyes, respiratory system and skin .
R33:Danger of cumulative effects.
Safety Statements 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  DO2625000
8-10-23
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29373100
Safety Profile
Human poison by subcutaneous route. Experimental poison by ingestion, skin contact, subcutaneous, intraperitoneal, intravenous, and intramuscular routes. Human systemic effects: cardiomyopathy includmg infarction, arrhythmias. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Used as an adrenergic, sympathomimetic, vasoconstrictor, bronchodilator, and cardiac stimulant.
Hazardous Substances Data 51-43-4(Hazardous Substances Data)
Toxicity
LD50 i.p. in mice: 4 mg/kg (Lands)

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