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77-86-1

Name Trometamol
CAS 77-86-1
EINECS(EC#) 201-064-4
Molecular Formula C4H11NO3
MDL Number MFCD00004679
Molecular Weight 121.14
MOL File 77-86-1.mol

Chemical Properties

Appearance White, crystalline solid. PH (0.1M aqueous solution) 10.6, corrosive to copper, brass, aluminum. Solubility in water 80 g/100 cc (20C). Combustible.
Melting point  167-172 °C(lit.)
Boiling point  219-220 °C10 mm Hg(lit.)
density  1,353 g/cm3
vapor pressure  0.0267 hPa (20 °C)
refractive index  1.4170 (estimate)
Fp  219-220°C/10mm
storage temp.  2-8°C
solubility  H2O: 4 M at 20 °C, clear, colorless
form  crystalline
color  white
Stability: Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
pka 8.1(at 25℃)
PH Range 7 - 9
PH 10.5-12.0(4 m in water, 25 °C)
Water Solubility  550 g/L (25 ºC)
Sensitive  Hygroscopic
λmax λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08
Detection Methods T,NMR,MS
Merck  14,9772
BRN  741883
InChIKey LENZDBCJOHFCAS-UHFFFAOYSA-N
Uses

tromethamine can help mask odor in a formulation. It is also used as a buffer, keeping product pH stable.

CAS DataBase Reference 77-86-1(CAS DataBase Reference)
NIST Chemistry Reference 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System 77-86-1(EPA Substance)

Safety Data

Hazard Codes  Xi
Risk Statements 

R36/37/38:Irritating to eyes, respiratory system and skin .

Safety Statements 

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .

WGK Germany  2
RTECS  TY2900000
3
TSCA  Yes
HazardClass  IRRITANT
HS Code  29221980
Hazardous Substances Data 77-86-1(Hazardous Substances Data)
Toxicity

LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rat > 5000 mg/kg

Raw materials And Preparation Products

Hazard Information

Material Safety Data Sheet(MSDS)

Questions And Answer

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