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75-25-2

Name Bromoform
CAS 75-25-2
EINECS(EC#) 200-854-6
Molecular Formula CHBr3
MDL Number MFCD00000128
Molecular Weight 252.73
MOL File 75-25-2.mol

Chemical Properties

Appearance colourless to yellow liquid
Melting point  8 °C
Boiling point  150 °C
density  2.89 g/mL at 25 °C(lit.)
vapor density  8.7 (vs air)
vapor pressure  5 mm Hg ( 20 °C)
refractive index  n20/D 1.595(lit.)
Fp  148-150°C
storage temp.  0-6°C
solubility  water: soluble800 part(lit.)
form  Liquid
pka 13.7(at 25℃)
color  White to off-white
Odor Chloroform-like odor
Stability: Stability May be an explosion hazard, especially when heated. Stable, but light-sensitive. Non-flammable. Incompatible with chemically active metals, strong bases. May contain ca 1% ethanol or 1-pentene (amylene) as a stabilizer.
Water Solubility  slightly soluble, 0.301 g/100 mL
Sensitive  Light Sensitive
Merck  14,1420
BRN  1731048
Henry's Law Constant 3.36 at 20.0 °C, 7.09 at 35.0 °C, 20.5 at 50.0 °C (equilibrium static cell, Wright et al., 1992)
Dielectric constant 4.4(20℃)
Exposure limits NIOSH REL: TWA 0.5 ppm (5 mg/m3), IDLH 85e respiratory irritation (Patnaik, 1992).
InChIKey DIKBFYAXUHHXCS-UHFFFAOYSA-N
LogP 2.400
CAS DataBase Reference 75-25-2(CAS DataBase Reference)
IARC 3 (Vol. 52, 71) 1999
NIST Chemistry Reference Methane, tribromo-(75-25-2)
EPA Substance Registry System 75-25-2(EPA Substance)

Safety Data

Hazard Codes  T,N,F
Risk Statements 
R23:Toxic by inhalation.
R36/38:Irritating to eyes and skin .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R22:Harmful if swallowed.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.
Safety Statements 
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36/37:Wear suitable protective clothing and gloves .
S16:Keep away from sources of ignition-No smoking .
S7:Keep container tightly closed .
RIDADR  UN 2515 6.1/PG 3
WGK Germany  3
RTECS  PB5600000
8-10
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29033990
Safety Profile
Suspected carcinogen with experimental neoplastigenic data. A human poison by ingestion. Moderately toxic by intraperitoneal and subcutaneous routes. Human mutation data reported. A lachrymator. It can damage the liver to a serious degree and cause death. It has anesthetic properties simdar to those of chloroform, but is not sufficiently volatile for inhalation purposes and is far too toxic for human use. As a sedative and antitussive its medicinal application has resulted in numerous poisonings. Inhalation of small amounts causes irritation, provoking the flow of tears and saliva, and reddening of the face. Abuse can lead to adhction and serious consequences. Explosive reaction with crown ethers or potassium hydroxide. Violent reaction with acetone or bases. Incompatible with Li or NaK alloys. When heated to decomposition it emits hghly toxic fumes of Br-. See also BROMIDES.
Hazardous Substances Data 75-25-2(Hazardous Substances Data)
Toxicity
LD50 s.c. in mice: 7.2 mmol/kg (Kutob, Plaa)
IDLA 850 ppm

Hazard Information

Material Safety Data Sheet(MSDS)

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