Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
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2-Amino-2-(hydroxymethyl)-1,3-propanediol(77-86-1)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
2-Amino-2-(hydroxymethyl)-1,3-propanediol
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediol
2-Amino-2-(hydroxymethyl)propane-1,3-diol
Aminotris(hydroxymethyl)methane
Tham
Tris(hydroxymethyl)methylamine
Tromethanmin
CAS
77-86-1
Formula
C4H11NO3
Molecular Weight
121.14
EINECS
201-064-4
RTECS
TY2900000
RTECS Class
Drug
Merck
12,9902
Beilstein/Gmelin
741883
Beilstein Reference
4-04-00-01903
EC Class
irritant

Physical and Chemical Properties

Appearance
Crystalline mass or white, crystalline powder, slight characteristic amine odor, hygroscopic.
Solubility in water
Very soluble
Melting Point
131
Boiling Point
357
Vapor Pressure
2E-6 (25 C)
Density
1.328 g/cm3
pKa/pKb
6.22 (pKb)
Partition Coefficient
-1.38
Heat Of Vaporization
69.7 kJ/mol
Usage
In synth of surface-active agents, vulcanization accelerators, pharmaceuticals: titrimetric standard, as emulsifying agent for cosmetic creams & lotions, mineral oil & paraffin wax emulsions, leather dressings, emulsifying agent for textile specialties, polishes, cleaning compd, so-called sol oils.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage
Store in a cool, dry place. Keep away from acids. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Discard contaminated shoes.

Hazards Identification

Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
EC Risk Phrase
R 36/37/38
EC Safety Phrase
S 26 36

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Exposure Effects
Prolonged or repeated skin contact may cause dermatitis.
Poison Class
-

Fire Fighting Measures

Flash Point
170
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.

Stability and Reactivity

Disposal Code
28
Incompatibilities
Bases, oxidizing agents, acids, aldehydes, copper, brass, and aluminum.
Stability
Stable under normal temperatures and pressures.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Transport Information

HS Code
2922 19 80
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