Name
Phenethyl alcohol
CAS
60-12-8
Synonyms
2-PHENYLETHANOL
2-PHENYLETHYL ALCOHOL
AKOS BBS-00004355
BENZENEETHANOL
BENZYL CARBINOL
BETA PHENYL ETHYL ALCOHOL
B-HYDROXYETHYLBENZENE
FEMA 2858
PEA
PHENETHYL ALCOHOL
PHENYL ETHANOL
PHENYLETHANOL,2-
PHENYL ETHYL ALCHOL
PHENYL ETHYL ALCOHOL
RARECHEM AL BD 0140
(beta-pea)
.beta.-Phenylethanol
1-Phenyl-2-ethanol
2-PEA
2-Phenethanol
EINECS(EC#)
200-456-2
Molecular Formula
C8H10O
MDL Number
MFCD00002886
Molecular Weight
122.16
MOL File
60-12-8.mol

Appearance
colourless liquid
mp 
−27 °C(lit.)

bp 
219-221 °C750 mm Hg(lit.)

density 
1.020 g/mL at 20 °C(lit.)

vapor density 
4.21 (vs air)

vapor pressure 
1 mm Hg ( 58 °C)

refractive index 
n20/D 1.5317(lit.)

FEMA 
2858
Fp 
216 °F

storage temp. 
Store at RT.
Stability:
Stable. Substances to be avoided include strong acids and strong oxidizing agents. Combustible.
Water Solubility 
20 g/L (20 ºC)
Merck 
14,7224
BRN 
1905732
Uses
phenethyl alcohol is used to mask odor and also as a preservative.
CAS DataBase Reference
60-12-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneethanol(60-12-8)
EPA Substance Registry System
60-12-8(EPA Substance)

Hazard Codes 
Xn
Risk Statements 
R21/22:Harmful in contact with skin and if swallowed .
R36/38:Irritating to eyes and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
RIDADR 

WGK Germany 
1

RTECS 
SG7175000

HazardClass 

PackingGroup 

HS Code 
29062990
Safety Profile
Moderately toxic by ingestion and skin contact. A skin and eye irritant. Experimental teratogenic effects. Other experimental reproductive effects. Causes severe central nervous system injury to experimental animals. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidzing materials. To fight fEe, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes
Hazardous Substances Data
60-12-8(Hazardous Substances Data)

Raw materials
Sodium hydroxide-->Sulfuric acid -->Sodium-->Nitrogen-->SULFURIC ACID-->Hydrogen-->ETHYLENE OXIDE-->Nickel-->Benzyl chloride-->Bromobenzene-->Benzeneacetonitrile-->Styrene-->2-Chloroethanol-->Aluminium chloride hexahydrate-->Sodium chlorate-->Sodium bromide-->Motor benzol-->Phenylacetic acid ethyl ester-->Styrene oxide-->FEMA 2771-->Geranium oil-->Rose Oil-->Air blower
Preparation Products
Propylene oxide-->Acetophenone-->Malathion-->Phenylacetaldehyde-->2,5-Dichloroaniline-->Diethyl maleate-->Rose Oil-->4-(2-Methoxyethyl)Phenol-->(2-Bromoethyl)benzene-->Benzyl salicylate-->[[p-(2-methoxyethyl)phenoxy]methyl]oxirane -->Phenethyl cinnamate-->Phenethyl butyrate-->(2-Methoxyethyl)benzene-->Phenethyl isobutyrate-->FEMA 3222-->Phenethyl acetate-->p-(2-Methoxyethyl) phenol-->PHENETHYL SALICYLATE-->FEMA 3632-->Phenethyl phenylacetate-->Metoprolol-->FEMA 2859-->Styralyl acetate-->CONVALLATOXIN-->PHENETHYL FORMATE-->2-PHENYLETHYL PROPIONATE-->FEMA 2871

msds information
β-phenylethyl alcohol(60-12-8).msds

Edible spices
Phenethyl alcohol is a kind of edible spices, and naturally exists in neroli, rose oil, geranium oil and other oils, because it has a soft, pleasant and persistent rose fragrance and is widely used in various kinds of flavors and cigarette flavor. It is dispensing rose scent, food additives, the main raw material for rose scent flavor, stable on alkali, which are widely used in soap fragrance, is essence blending all rose scent series of spices, because it does not dissolve in water, it is often used in the making up water, soap and orange flower, purple, etc. It is also used in the blending of flavor. Because the Phenethyl alcohol has a good antibacterial efficiency, it can be used in the ophthalmic solution. At present there are main three synthesis methods as following:
1, by styrene via halogenation, saponification, hydrogenation, distillation.
2, and microorganism fermentation in yeast by bioconversion.
3, calcium carbide, benzene as raw material preparation of benzyl ethanol, reaction equations are as follows:
1)CaC2+2H2O=Ca(OH)2+C2H2
2)C6H6+C2H2=C6H6CHCH2（Styrene）
3)C6H6CHCH2＋H2O=C6H6CH2CH2OH（Phenylethyl alcohol）
Chemical Properties
Phenethyl alcohol is a clear, colorless liquid with an odor of rose oil. It has a burning taste that irritates and then anesthetizes mucous membranes.

Phenethyl Alcohol (PEA) is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations. It is active at pH 6 or less and is inactivated by nonionic detergents including polysorbate-80. PEA is also a widely used fragrance material that imparts a rose character to perfume compositions. Almost all rose fragrances and other floral-type perfumes contain PEA, and PEA is used extensively for many other fragrance applications because it blends ell.
PEA is metabolized to phenylacetic acid in mammals. In humans, it is excreted in urine as the conjugate phenylacetylglutamine.
Uses
Phenylethyl alcohol is qualitatively and quantitatively one of the most important fragrance substances that belongs to the class of araliphatic alcohols.
Phenylethyl alcohol is used frequently and in large amounts as a fragrance material. It is a popular component in rose-type compositions, but it is also used in other blossom notes. It is stable to alkali and, therefore, ideally suited for use in soap perfumes.
Production
Many syntheticmethods are known for preparing phenylethyl alcohol; the following are currently of industrial importance:
1) Friedel–Crafts reaction of benzene and ethylene oxide: In the presence of molar quantities of aluminum chloride, ethylene oxide reacts with benzene to give an addition product, which is hydrolyzed to phenylethyl alcohol:

Formation of by-products, such as 1,2-diphenylethane, is largely avoided by using an excess of benzene at low temperature. Special purification procedures are required to obtain a pure product that is free of chlorine and suitable for use in perfumery.
2) Hydrogenation of styrene oxide: Excellent yields of phenylethyl alcohol are obtainedwhen styrene oxide is hydrogenated at low temperature, using Raney nickel as a catalyst and a small amount of sodium hydroxide.

Spectrum Detail
Phenethyl alcohol(60-12-8) MS
Phenethyl alcohol(60-12-8) IR2
Phenethyl alcohol(60-12-8) Raman
Phenethyl alcohol(60-12-8) ¹³C NMR
Phenethyl alcohol(60-12-8) ¹H NMR
Phenethyl alcohol(60-12-8) IR1

Acros Organics
Phenethyl alcohol, 99+%(60-12-8)
Alfa Aesar
2-Phenylethanol, 98+%(60-12-8)
Sigma Aldrich
60-12-8(sigmaaldrich)
TCI AMERICA
2-Phenylethyl Alcohol,>98.0%(GC)(60-12-8)