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Name Adipic acid
CAS 124-04-9
EINECS(EC#) 204-673-3
Molecular Formula C6H10O4
MDL Number MFCD00004420
Molecular Weight 146.14
MOL File 124-04-9.mol

Chemical Properties


Adipic acid is a white crystalline solid/crystalline granule, and its odour has not been characterised. It is stable and incompatible with ammonia and strong oxidising agents. It may form combustible dust concentrations in air. The likely routes of exposure to workers are by skin contact and inhalation at workplaces. It is used in the manufacture of nylon, plasticisers, urethanes, adhesives, and food additives.

Appearance Adipic acid is a combustible, white, crystalline solid or powder. Odorless.
Melting point  151-154 °C(lit.)
Boiling point  265 °C100 mm Hg(lit.)
density  1,36 g/cm3
vapor density  5 (vs air)
vapor pressure  1 mm Hg ( 159.5 °C)
refractive index  1.4880
FEMA  2011
Fp  385 °F
storage temp.  Store below +30°C.
solubility  methanol: 0.1 g/mL, clear, colorless
form  Solid
pka 4.43(at 25℃)
color  White
Stability: Stable. Substances to be avoided include ammonia, strong oxidizing agents.
PH 2.7 (23g/l, H2O, 25℃)
Water Solubility  1.44 g/100 mL (15 ºC)
Merck  14,162
JECFA Number 623
BRN  1209788

Adipic Acid is an acidulant and flavoring agent. it is characterized as stable, nonhygroscopic, and slightly soluble, with a water solubility of 1.9 g/100 ml at 20°c. it has a ph of 2.86 at 0.6% usage level at 25°c. it is used in powdered drinks, beverages, gelatin desserts, loz- enges, and canned vegetables. it is also used as a leavening acidulant in baking powder. it can be used as a buffering agent to maintain acidities within a range of ph 2.5–3.0. it is occasionally used in edi- ble oils to prevent rancidity.

CAS DataBase Reference 124-04-9(CAS DataBase Reference)
NIST Chemistry Reference Hexanedioic acid(124-04-9)
EPA Substance Registry System 124-04-9(EPA Substance)

Safety Data

Hazard Codes  Xi
Risk Statements 

R36:Irritating to the eyes.

Safety Statements 

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .

WGK Germany  1
RTECS  AU8400000
Autoignition Temperature 788 °F
HS Code  29171210
storage Adipic acid should be kept stored in a tightly closed container, in a cool, dry, ventilated area and protected against physical damage. In storage, adipic acid should be isolated from incompatible substances and dust formation and ignition sources should be avoided.
Precautions Occupational workers should avoid contact of the adipic acid with the eyes, avoid breathing dust, and keep the container closed. Workers should use adipic acid only with adequate ventilation. Workers should wash thoroughly after handling adipic acid and keep away from heat, sparks, and flame. Also, workers should use rubber gloves and laboratory coats, aprons, or coveralls, and avoid creating a dust cloud when handling, transferring, and cleaning up.
Safety Profile

Poison by intraperitoneal route. Moderately toxic by other routes. A severe eye irritant. Combustible when exposed to heat or flame; can react with oxidzing materials. When heated to decomposition it emits acrid smoke and fumes.

Hazardous Substances Data 124-04-9(Hazardous Substances Data)

LD50 orally in Rabbit: 5700 mg/kg LD50 dermal Rabbit > 7940 mg/kg

Hazard Information

Material Safety Data Sheet(MSDS)

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