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Name Dimethyl adipate
CAS 627-93-0
EINECS(EC#) 211-020-6
Molecular Formula C8H14O4
MDL Number MFCD00008469
Molecular Weight 174.19
MOL File 627-93-0.mol

Chemical Properties


Dimethyl adipate (DMA) is a colourless and flammable liquid. It is soluble in alcohol and ether but sparingly soluble in water. DMA is incompatible with strong oxidising agents, and on decomposition, it emits carbon monoxide, irritating and toxic fumes and gases, and carbon dioxide. DMA reacts with acids, alkalis, and strong oxidants. DMA is synthesised by the esterification of adipic acid. DMA is part of a dibasic ester (DBE) blend used as a major ingredient in several paint strippers, and the DBE blends used in paint stripping formulations contain a major portion (about 90%) of DMA. DMA is used as a chemical intermediate (polymers, agrochemicals), cellulose resins, a speciality solvent (inks, coatings, adhesives), and an emollient and can also be utilised as a paint remover and plasticiser.

Appearance colourless liquid
Melting point  8 °C (lit.)
Boiling point  109-110 °C/14 mmHg (lit.)
density  1.062 g/mL at 20 °C(lit.)
vapor pressure  0.2 mm Hg ( 20 °C)
refractive index  n20/D 1.428(lit.)
Fp  225 °F
storage temp.  Store below +30°C.
solubility  <1g/l
form  Liquid
color  Clear
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases reducing agents.
explosive limit 0.81-8.1%(V)
Water Solubility  Miscible with alcohols and ether. Immiscible with water.
JECFA Number 1964
Merck  14,162
BRN  1707443
CAS DataBase Reference 627-93-0(CAS DataBase Reference)
NIST Chemistry Reference Hexanedioic acid, dimethyl ester(627-93-0)
EPA Substance Registry System 627-93-0(EPA Substance)

Safety Data

Safety Statements 

S24/25:Avoid contact with skin and eyes .

WGK Germany  1
RTECS  AV1645000
Autoignition Temperature 680 °F
HS Code  29171290
Precautions During handling of dimethyl adipate, occupational workers should be careful and use self-contained breathing apparatus, rubber boots, and heavy rubber gloves and avoid prolonged period of exposures. Workers should avoid contact of dimethyl adipate with skin, eyes and nose.
Safety Profile

Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

Hazardous Substances Data 627-93-0(Hazardous Substances Data)

LD50 orally in Rabbit: 8191 mg/kg LD50 dermal Rabbit > 2250 mg/kg

Raw materials And Preparation Products

Hazard Information

Material Safety Data Sheet(MSDS)

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