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tert-Butyl bromoacetate

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tert-Butyl bromoacetate Basic information
tert-Butyl bromoacetate Chemical Properties
Safety Information
  • Hazard Codes Xi,F
  • Risk Statements 10-36/37/38
  • Safety Statements 26-24/25-16
  • RIDADR UN 1993 3/PG 3
  • WGK Germany 3
  • 19
  • Hazard Note Irritant/Flammable/Lachrymatory
  • TSCA T
  • HazardClass 3
  • PackingGroup III
  • HS Code 29159080
MSDS
tert-Butyl bromoacetate Usage And Synthesis
  • Chemical Propertiesclear colorless to yellow liquid
  • Usestert-Butyl Bromoacetate is a halogenated t-butyl acetate commonly used as an alkylating agent. tert-Butyl Bromoacetate is used in the synthesis of collagenase inhibitors.
  • Purification MethodsDissolve the ester in Et2O, wash it well with ice cold 10% aqueous K2CO3, dry it over CaCl2, filter and evaporate the Et2O, then fractionate it through a Vigreux column (p 11) in a vacuum. LACHRYMATORY. [Abramovitch et al. J Am Chem Soc 64 2274 1942, Abramovitch & Hauser J Am Chem Soc 65 986 1943, Beilstein 2 III 482.]
tert-Butyl bromoacetate Preparation Products And Raw materials
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