D-谷氨酸
D-谷氨酸 性质
| 熔点 | 200-202 °C (subl.)(lit.) |
|---|---|
| 比旋光度 | -31.3 º (c=10, 2 N HCl) |
| 沸点 | 267.21°C (rough estimate) |
| 密度 | 1.5380 |
| 折射率 | 1.4210 (estimate) |
| 储存条件 | Keep in dark place,Sealed in dry,Room Temperature |
| 溶解度 | 可微溶于水 |
| 形态 | 粉末 |
| 酸度系数(pKa) | pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C) |
| 颜色 | 白色至类白色 |
| 水溶解性 | 7 g/L (20 ºC) |
| Merck | 14,4469 |
| BRN | 1723800 |
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| LogP | -0.969 (est) |
| CAS 数据库 | 6893-26-1(CAS DataBase Reference) |
| NIST化学物质信息 | D-Glutamic acid(6893-26-1) |
| EPA化学物质信息 | D-Glutamic acid (6893-26-1) |
D-谷氨酸 用途与合成方法
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Human Endogenous Metabolite
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Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
MSDS信息
D-谷氨酸 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | A14191 | D-谷氨酸, 99+% | 6893-26-1 | 5g | 451 |
| 2024-11-08 | A14191 | D-谷氨酸, 99+% | 6893-26-1 | 25g | 1407 |
