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Lanoconazole

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Lanoconazole Basic information
Lanoconazole Chemical Properties
  • Melting point:141.50C
  • Boiling point:477.6±55.0 °C(Predicted)
  • Density 1.43±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka3.76±0.10(Predicted)
  • form neat
  • CAS DataBase Reference101530-10-3(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22
  • WGK Germany 3
  • RTECS NI3393500
  • ToxicityLD50 in male, female mice, rats (mg/kg): 3224, 2715, 993, 652 orally; 2158, 1743, 1655, 2596 i.p.; >5000 both species s.c.; LD50 dermally in rats: >5000 mg/kg (Munt)
MSDS
Lanoconazole Usage And Synthesis
  • DescriptionLanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.
  • Chemical PropertiesLight-Yellow Crystals
  • OriginatorNihon Nohyaku (Japan)
  • UsesAntifungal
  • brand nameAstat
Lanoconazole Preparation Products And Raw materials
Lanoconazole(101530-10-3)Related Product Information
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