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4-Aminophenylarsonic acid

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4-Aminophenylarsonic acid Basic information
4-Aminophenylarsonic acid Chemical Properties
  • Melting point:≥300 °C(lit.)
  • Boiling point:528.5±52.0 °C(Predicted)
  • Density 1.9571
  • form solid
  • pkapK1: ca 2;pK2: 4.02;pK3: 8.62 (25°C)
  • color Needles from aq solns
  • Merck 14,792
  • BRN 1102334
  • CAS DataBase Reference98-50-0(CAS DataBase Reference)
  • EPA Substance Registry Systemp-Aminobenzenearsonic acid (98-50-0)
Safety Information
4-Aminophenylarsonic acid Usage And Synthesis
  • Chemical Propertiesoff-white fine crystalline powder
  • Chemical Propertiesp-Arsanilic acid is an off-white powder. It is slightly soluble in cold water. It is incompatible with oxidizing agents; on hazardous decomposition, p-arsanilic acid produces nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen gas, and oxides of arsenic.
  • Uses4-Aminophenylarsonic acid is an organoarsenic compound. 4-Aminophenylarsonic acid is a highly toxic contaminant and can be found in plants growing in contaminated soil. 4-Aminophenylarsonic acid was used as an additive in animal feed. It has also been used in treating dysentery in swine as well as having potential chemotherapeutic activity.
  • Usesantiulcer
  • Usesmanufacture of medicinal arsenicals.
  • HazardToxic.
  • Health HazardOccupational workers exposed to p-arsanilic acid develop poisoning. The symptoms include, but are not limited to, eye and skin irritation, chemical conjunctivitis and corneal damage, hyperpigmentation of the skin and, perkeratoses of plantar and palmar surfaces, primary irritation and sensitization, digestive tract irritation, gastrointestinal hypermotility, diarrhea, hepatitis, hepatocellular necrosis, central nervous system depression, cardiac disturbances, and liver and kidney damage. The target organs include the kidneys, central nervous system, liver, and cardiovascular system. After a prolonged period of exposure to arsenic compounds, including arsenical dust, workers are known to develop shortness of breath, nausea, chest pains, garlic odor, and impairment of peripheral circulation. The toxicological properties of p-arsanilic acid have not been fully investigated.
  • Safety ProfilePoison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Flammable, decomposes with heat to yield flammable vapors. When heated to decomposition or on contact with acid or acid fumes it emits highly toxic fumes of As and NO,. See also ARSENIC COMPOUNDS and ANILINE.
  • storagep-Arsanilic acid should be kept stored in a tightly closed container in a cool, dry, wellventilated area. It should be kept away from incompatible materials, dust generation, excess heat, and strong oxidants.
  • Purification MethodsCrystallise it from water or ethanol/ether. POISONOUS. [Beilstein 16 I 466.]
  • PrecautionsOccupational workers should wash thoroughly after using p-arsanilic acid. Any contaminated clothing should be washed before reuse. Work areas should have adequate ventilation and minimum dust generation and accumulation. Workers should avoid any kind of contact of p-arsanilic acid with the eyes, skin, clothing, ingestion or inhalation.
4-Aminophenylarsonic acid Preparation Products And Raw materials
4-Aminophenylarsonic acid(98-50-0)Related Product Information
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  • Company Name:Chengdu Ai Keda Chemical Technology Co., Ltd. Gold
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  • Company Name:J & K SCIENTIFIC LTD.
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  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
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  • Company Name:Arden pharmaceutical &chemical Co., Ltd
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