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Copper(II) gluconate

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Copper(II) gluconate Basic information
Copper(II) gluconate Chemical Properties
Safety Information
Copper(II) gluconate Usage And Synthesis
  • DescriptionCopper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.
  • ReferencesDicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
    Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
    Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
  • Chemical PropertiesCopper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.
  • UsesSupplement (trace mineral).
  • Usescopper gluconate is cited as having skin-conditioning and skinprotecting functions.
  • PreparationCopper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.
  • Safety ProfileWhen heated to decomposition it emits acrid smoke and irritating fumes.
Copper(II) gluconate Preparation Products And Raw materials
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