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Pyridoxal hydrochloride

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Pyridoxal hydrochloride Basic information
Pyridoxal hydrochloride Chemical Properties
  • Melting point:173 °C (dec.)(lit.)
  • storage temp. −20°C
  • form Powder
  • color White
  • Water Solubility Soluble in water and ethanol.
  • Sensitive Hygroscopic
  • Merck 14,7978
  • BRN 3656994
  • InChIKeyFCHXJFJNDJXENQ-UHFFFAOYSA-N
  • CAS DataBase Reference65-22-5(CAS DataBase Reference)
  • EPA Substance Registry SystemPyridoxal hydrochloride (65-22-5)
Safety Information
MSDS
Pyridoxal hydrochloride Usage And Synthesis
  • Chemical PropertiesWhite to off-white crystalline powder
  • UsesFor the labeling of amino acids and their detection in picomolar amounts1; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate2
  • UsesPyridoxal is one of the three natural forms of vitamin B6, along with pyridoxamine and pyridoxine. All of these forms are converted in the human body into a single biologically active form, Pyridoxal 5-phosphate (P991715). Green plants are a natural source of Pyridoxal, and its deficiency in the human body can lead to serious complications such as epilepsy and seizures.
  • DefinitionChEBI: A hydrochloride obtained by combining pyridoxal with one molar equivalent of hydrochloric acid.
  • Safety ProfilePoison by intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ALDEHYDES.
  • Purification MethodsDissolve it in water and adjust the pH to 6 with NaOH. Set aside overnight to crystallise. The crystals are washed with cold water, dried in a vacuum desiccator over P2O5 and stored in a brown bottle at room temperature. The free base is then converted to the hydrochloride with one equivalent of HCl. [Fleck & Alberty J Phys Chem 66 1678 1962, Beilstein 21/13 V 44.]
Pyridoxal hydrochloride Preparation Products And Raw materials
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