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Pyridoxamine dihydrochloride

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Pyridoxamine dihydrochloride Basic information
Pyridoxamine dihydrochloride Chemical Properties
  • Melting point:224-226 °C (dec.)(lit.)
  • Density 1.4025 (rough estimate)
  • refractive index 1.6100 (estimate)
  • storage temp. −20°C
  • form Powder or Solid
  • pkapKa 3.31(H2O t = 25 I = 0.1)(Approximate)
  • color White to off-white to pale brown
  • Water Solubility Soluble in DMSO, water, or methanol /n
  • Merck 7980
  • BRN 3632748
  • CAS DataBase Reference524-36-7(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36
  • WGK Germany 2
  • RTECS UV1230000
  • HazardClass IRRITANT
  • HS Code 29333990
MSDS
Pyridoxamine dihydrochloride Usage And Synthesis
  • Chemical PropertiesWhite crystalline powder
  • DefinitionChEBI: A hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy.
  • Purification MethodsThe amine salt is crystallised from hot MeOH. The free base crystallises from EtOH with m 193-193.5o [Harris et al. J Biol Chem 154 315 1944, J Am Chem Soc 66 2088 1944]. [Beilstein 22 IV 6064, 22/12 V 324.]
Pyridoxamine dihydrochloride Preparation Products And Raw materials
Pyridoxamine dihydrochloride(524-36-7)Related Product Information
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