Potassium persulfate complex salt (oxone) preparation:
(1) making the pill core 1: dissolve the No.1 plasticizer and sodium carboxymethyl cellulose in water to obtain the mixture A, mix potassium bisulfate and the filler, mix with the mixture A sufficiently, and then dry to obtain the pill core 1;
(2) Synthesis of the inner film coat solution: add ethyl cellulose to the organic solvent, heat in a water bath, stir, add No. 2 plasticizer and porosity-inducing agent, and stir until the ethyl cellulose is dissolved, to obtain the inner film coat solution;
(3) Synthesize the outer layer film coat solution: add hydroxypropyl methyl cellulose and potassium persulfate into water, carry out water bath heating, and then add No.3 plasticizer, stir until hydroxypropyl methyl cellulose dissolves, and obtain the outer layer film coat solution;
(4) coating: the drug-carrying pill core 1 is repeatedly immersed into the inner membrane coating solution, removed, and then repeatedly immersed into the outer membrane coating solution, removed, shaken, filtered, and subjected to vacuum drying treatment until constant weight, to obtain a slow-release potassium persulfate preparation.
