Sulfaquinoxaline is a kind of veterinary medicine which can be used for the treatment of coccidiosis in cattle and sheep. It is usually used in combination with Amprolium and Vitamin K. It is a protective agent against upper respiratory infections of poultry and a prophylactic against coccidiosis. It takes effects via inhibiting vitamin K epoxidase (epoxide reductase, menadione epoxide reductase) and quinone reductase. Sulfaquinoxaline played an important part in the demotion of roast chicken from vaunted Sunday-dinner status to an un-respected position on the everyday menu of the Western world. Although it has long been eclipsed by other drugs in poultry management, it continues to be used in other host species.
Campbell, W. C. "History of the discovery of sulfaquinoxaline as a coccidiostat." Journal of Parasitology 94.4(2008):934-945.
ChEBI: 4-amino-N-(2-quinoxalinyl)benzenesulfonamide is a sulfonamide and a member of benzenes.
Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and SOx.
