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Lithium acetate

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Lithium acetate Basic information
Lithium acetate Chemical Properties
  • Melting point:283-285 °C(lit.)
  • solubility H2O: 5 M at 20 °C, clear, colorless
  • form Powder or Crystals
  • color White to yellow
  • Water Solubility 40.8 g/100 mL (20 ºC)
  • Merck 14,5521
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • CAS DataBase Reference546-89-4(CAS DataBase Reference)
  • EPA Substance Registry SystemAcetic acid, lithium salt(546-89-4)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36
  • Safety Statements 23-24/25-39-26-22
  • WGK Germany 1
  • RTECS AI5450000
  • TSCA Yes
  • HS Code 29152990
Lithium acetate Usage And Synthesis
  • DescriptionLithium acetate (CH3COOLi) is a salt of lithium and acetic acid.
  • Chemical Propertiessolid
  • UsesLithium acetate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It has a lower electrical conductivity and can be run at higher speeds than can gels made from TAE buffer (5-30V/cm as compared to 5 - 10 V / cm). Lithium boric acid or sodium boric acid are usually preferable to lithium acetate or TAE when analyzing smaller fragments of DNA (less than 500 bp) due to the higher resolution of borate-based buffers in this size range as compared to acetate buffers.
    Lithium acetate is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is believed that the beneficial effect of LiAc is caused by its chaotropic effect denaturing both DNA, RNA and proteins.
  • DefinitionChEBI: An acetate salt comprising equal numbers of acetate and lithium ions.
  • Safety ProfilePoison by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALUMINUM and LITHIUM COMPOUNDS.
Lithium acetate Preparation Products And Raw materials
Lithium acetate(546-89-4)Related Product Information
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