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Chlorotributyltin

Basic information Description References Safety Related Supplier
Chlorotributyltin Basic information
Chlorotributyltin Chemical Properties
  • Melting point:-9 °C
  • Boiling point:171-173 °C25 mm Hg(lit.)
  • Density 1.2 g/mL at 25 °C(lit.)
  • vapor pressure <0.01 mm Hg ( 20 °C)
  • refractive index n20/D 1.492(lit.)
  • Flash point:>230 °F
  • storage temp. 2-8°C
  • solubility 0.017g/l
  • form liquid
  • color colorless
  • Specific Gravity1.186
  • Water Solubility PRACTICALLY INSOLUBLE
  • Sensitive Moisture Sensitive
  • BRN 3535715
  • InChIKeyGCTFWCDSFPMHHS-UHFFFAOYSA-M
  • CAS DataBase Reference1461-22-9(CAS DataBase Reference)
  • NIST Chemistry ReferenceTri-n-butyltin chloride(1461-22-9)
  • EPA Substance Registry SystemTributyltin chloride (1461-22-9)
Safety Information
MSDS
Chlorotributyltin Usage And Synthesis
  • DescriptionChlorotributyltin is the chloride of tributyltin. It is a biocide that contaminates foods, especially shellfish. It is an endocrine disrupter in several marine species and is neurotoxic and immuno-toxic in mammals. It has been used as a heat stabilizer, agricultural pesticide and component of antifouling paints2. However, it is perhaps the most acutely toxic chemical to aquatic organisms ever deliberately introduced to water. It has been demonstrated to have an adverse effect on shellfish in France and England, and as a consequence the use of tributyltin‐containing antifouling paints has been restricted in these countries. Other countries have banned the use of tributyltin‐containing antifouling paints or are contemplating restrictions3.
  • References
    1. Cooke, G. M., et al. Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association 42.2(2004):211-220.
    2. Nakatsu, Yusuke, Y. Kotake, and S. Ohta. "Tributyltin-induced cell death is mediated by calpain in PC12 cells."Neurotoxicology 27.4(2006):587-593.
    3. Maguire, R. James. "Environmental aspects of tributyltin." Applied Organometallic Chemistry 1.6(1987):475-498.
  • Chemical PropertiesColorless liquid. Soluble in the common organic solvents; including alcohol, heptane, benzene, and toluene; insoluble in cold water, but hydrolyzes in hot water.
  • UsesTributyltin Chloride is a triorganotin compound with insecticidal acitivity. Tributyltin Chloride is an endocrine disruptor as well as an inhibitor for the V-ATPases (potential targets in the treatmen t of diseases such as osteoporosis and cancer).
  • HazardA poison by ingestion and skin contact. A severe eye irritant. Tributyl tin compounds are extremely toxic to marine life.
Chlorotributyltin Preparation Products And Raw materials
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