Glykolsaeure

Bezeichnung:Glykolsaeure

CAS-Nr79-14-1

Englisch Name:Glycolic acid

CBNumberCB9463563

SummenformelC2H4O3

Molgewicht76.05

MOL-Datei79-14-1.mol

Synonyma

Glykolsaeure

Glykols?ure

alpha-Hydroxyessigs?ure

Glykolsaeure physikalisch-chemischer Eigenschaften

Schmelzpunkt	75-80 °C (lit.)
Siedepunkt	112 °C
chüttdichte	600kg/m3
Dichte	1.25 g/mL at 25 °C
Dampfdruck	10.8 hPa (80 °C)
Brechungsindex	n20/D 1.424
Flammpunkt	112°C
storage temp.	Store below +30°C.
Löslichkeit	H₂O: 0.1 g/mL, clear
pka	3.83(at 25℃)
Aggregatzustand	Solution
Farbe	White to off-white
PH	2 (50g/l, H2O, 20℃)
Geruch (Odor)	at 100.00 %. odorless very mild buttery
Geruchsart	buttery
Wasserlöslichkeit	SOLUBLE
Spezifische Wärmekapazität	Cp(gas): 1.15 J/(g·K), at 25℃
Sensitive	Hygroscopic
Merck	14,4498
BRN	1209322
Henry's Law Constant	2.8×10² mol/(m³Pa) at 25℃, Burkholder et al. (2019)
Stabilität	Stable. Incompatible with bases, oxidizing agents and reducing agents.
Kosmetik-Inhaltsstoffe Funktionen	BUFFERING
Erinnerung an die inhaltsstoffe	Glycolic acid (79-14-1)
InChI	1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChIKey	AEMRFAOFKBGASW-UHFFFAOYSA-N
SMILES	OCC(O)=O
LogP	-1.07 at 20℃
CAS Datenbank	79-14-1(CAS DataBase Reference)
NIST chemische Informationen	Acetic acid, hydroxy-(79-14-1)
EPA chemische Informationen	Glycolic acid (79-14-1)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34-22-20
S-Sätze:	26-36/37/39-45-23
RIDADR	UN 3265 8/PG 3
WGK Germany	1
RTECS-Nr.	MC5250000
TSCA	TSCA listed
HS Code	2918 19 98
HazardClass	8
PackingGroup	II
Speicherklasse	8A - Combustible corrosive hazardous materials
Hazard Classifications	Acute Tox. 4 Inhalation Eye Dam. 1 Skin Corr. 1B
Giftige Stoffe Daten	79-14-1(Hazardous Substances Data)
Toxizität	LD50 orally in rats: 1.95 g/kg, H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941)

Gefahreninformationscode (GHS)

Glycolic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE HYGROSKOPISCHE KRISTALLE.
CHEMISCHE GEFAHREN
Reagiert mit starken Oxidationsmitteln, Cyaniden und Sulfiden. Reagiert sehr heftig mit Aluminium, Zink und Zinn unter Feuer- und Explosionsgefahr. Mittelstarke Säure in wässriger Lösung.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Eine gesundheitsschädliche Partikelkonzentration in der Luft kann beim Versprühen oder Dispergieren schnell erreicht werden, besonders als Pulver.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz verätzt die Haut und die Augen, und reizt die Atemwege. ätzend beim Verschlucken. Möglich sind Auswirkungen auf die Nieren mit nachfolgendem Nierenversagen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.
LECKAGE
Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät. Verschüttetes Material in abgedeckten Behältern sammeln.
R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
Chemische Eigenschaften
Glycolic acid, CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF). It is soluble in water,alcohol,and ether.Glycolic acid is used in dyeing, tanning, electropolishing,and in foodstuffs. It is produced by oxidizing glycol with dilute nitric acid.
Verwenden
In the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.
Verwenden
glycolic acid (hydroxyacetic acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles. glycolic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells. It also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water. This occurs in the cellular cement through an activation of glycolic acid and the skin’s own hyaluronic acid content. Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by glycolic acid. As a result, the skin’s own ability to raise its moisture content is increased. glycolic acid is the simplest alpha hydroxyacid (AHA). It is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight. It is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH. glycolic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes. It is also used for diminishing the signs of age spots, as well as actinic keratosis. However, glycolic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles. Regardless of the G skin type, glycolic acid use is associated with softer, smoother, healthier, and younger looking skin. glycolic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
synthetische
There are different preparation methods to synthesize glycolic acid. However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less. It can be prepared when chloroacetic acid reacts with sodium hydroxide and undergoes re-acidification. Electrolytic reduction of oxalic acid also could synthesize this compound. Glycolic acid can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes. It can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.
Definition
ChEBI: A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
benefits
Glycolic acid addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.
Flammability and Explosibility
Non flammable
Nebenwirkungen
Common side effects of Glycolic acid include dry skin, erythema (skin redness), burning sensation, itching, skin irritation, and skin rash. It can make the skin more sensitive in the sunlight, hence always use sunscreen and protective clothing before you step outdoors.
Source
Glycolic acid is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
läuterung methode
Crystallise it from diethyl ether. [Beilstein 3 IV 571.]
Filter für giftige stoffe
The initial threshold screening level for hydroxy acetic acid is 4 μg/m3 based on an annual averaging time.

Glycolic acid Upstream-Materialien And Downstream Produkte

Glykolsaeure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

79-14-1, Glycolic acid Verwandte Suche:

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