Dopexamine hydrochloride

Dopexamine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White or almost white, crystalline powder.

• Verwenden

  Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine hydrochloride has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.

• Verwenden

  Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.

• Trademarks

  Dopacard (Fisons).

• Clinical Use

  Inotropic support in exacerbations of heart failure and heart failure associated with cardiac surgery

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Anaesthetics: risk of ventricular arrhythmias with isoflurane - avoid.
  Antidepressants: risk of hypertensive crisis with MAOIs and moclobemide.
  Beta-blockers: risk of severe hypertension
  Dopaminergics: avoid with rasagiline.
  Sympathomimetics: effects of adrennoradrenaline possibly enhanced.

• Stoffwechsel

  Dopexamine is rapidly eliminated from blood with a halflife of approximately 6-7 minutes in healthy volunteers and around 11 minutes in patients with cardiac failure. Subsequent elimination of the metabolites is by urinary and biliary excretion.

Dopexamine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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