Ethenzamid

Bezeichnung:Ethenzamid

CAS-Nr938-73-8

Englisch Name:2-Ethoxybenzamide

CBNumberCB5689369

SummenformelC9H11NO2

Molgewicht165.19

MOL-Datei938-73-8.mol

Synonyma

Ethenzamid

Ethenzamid physikalisch-chemischer Eigenschaften

Schmelzpunkt	132-134 °C (lit.)
Siedepunkt	293.03°C (rough estimate)
Dichte	1.1603 (rough estimate)
Brechungsindex	1.5620 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Dichloromethane (Slightly)
pka	15.62±0.50(Predicted)
Aggregatzustand	Granular Crystalline Powder
Farbe	White to almost white
Wasserlöslichkeit	<0.1 g/100 mL at 16 ºC
Merck	14,3731
InChI	InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)
InChIKey	SBNKFTQSBPKMBZ-UHFFFAOYSA-N
SMILES	C(N)(=O)C1=CC=CC=C1OCC
CAS Datenbank	938-73-8(CAS DataBase Reference)
NIST chemische Informationen	Ethenzamide(938-73-8)
EPA chemische Informationen	Ethenzamide (938-73-8)

Sicherheit

S-Sätze:	24/25
WGK Germany	2
RTECS-Nr.	CU4381000
TSCA	TSCA listed
HS Code	29242995
Speicherklasse	11 - Combustible Solids
Toxizität	LD50 orally in mice: 1160 mg/kg (Starmer)

Gefahreninformationscode (GHS)

2-Ethoxybenzamide Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
WHITE TO ALMOST WHITE GRANULAR CRYSTALLINE POWDER
Originator
Ethenzamide,Tongxiang Hengda
Definition
ChEBI: Ethenzamide is an organic molecular entity.
Manufacturing Process
500 g of salicylic amide are dissolved in 1.5 L of 10% alcohol by means of 146 g of sodium hydroxide. 560 g diethyl sulphate are added, the mixture is frequently shaken during four hours and kept cold. 20 hours later the 2- ethoxy-benzamide is precipitated in a gritty state and is removed by suction and dried at 50°-100°C. The yield is 540 g or about 90%. MP: 130°C.
Therapeutic Function
Analgesic
Allgemeine Beschreibung
White or almost-white crystalline powder. Almost odorless. Tasteless.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
2-Ethoxybenzamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 2-Ethoxybenzamide emits toxic fumes of nitrogen oxides.
Brandgefahr
Flash point data for 2-Ethoxybenzamide are not available; however, 2-Ethoxybenzamide is probably combustible.
Clinical Use
Ethenzamide is a nonsteroidal anti-inflammatory drug used mainly in combination with other ingredients for the treatment of mild to moderate pain including musculoskeletal and joint disorders.
Einzelnachweise
[1] Tetrahedron Letters, 2017, vol. 58, # 43, p. 4090 - 4093
[2] Journal of Organic Chemistry, 2015, vol. 80, # 8, p. 4148 - 4151
[3] ChemCatChem, 2017, vol. 9, # 7, p. 1349 - 1353
[4] Patent: CN106588686, 2017, A. Location in patent: Paragraph 0023; 0025

2-Ethoxybenzamide Upstream-Materialien And Downstream Produkte

Ethenzamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

938-73-8, 2-Ethoxybenzamide Verwandte Suche:

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