2-Cyanacetamid

Bezeichnung:2-Cyanacetamid

CAS-Nr107-91-5

Englisch Name:2-Cyanoacetamide

CBNumberCB7852727

SummenformelC3H4N2O

Molgewicht84.08

MOL-Datei107-91-5.mol

Synonyma

2-Cyanacetamid

2-Cyanacetamid physikalisch-chemischer Eigenschaften

Schmelzpunkt	119-121 °C(lit.)
Siedepunkt	154.34°C (rough estimate)
Dichte	1,4 g/cm³
Brechungsindex	1.5110 (estimate)
Flammpunkt	419 °F
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	cold water: soluble1gm in 6.5ml
Aggregatzustand	Crystalline Powder
pka	-1.27±0.10(Predicted)
Farbe	White to light cream
Geruch (Odor)	Odorless
Wasserlöslichkeit	soluble
Merck	14,2688
BRN	878221
CAS Datenbank	107-91-5(CAS DataBase Reference)
NIST chemische Informationen	Acetamide, 2-cyano-(107-91-5)
EPA chemische Informationen	2-Cyanoacetamide (107-91-5)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38-20/21/22
S-Sätze:	22-26-28A
RIDADR	UN 3439 6.1/PG 3
WGK Germany	2
RTECS-Nr.	AB5950000
TSCA	Yes
PackingGroup	III
HS Code	29159080
HS Code	29269095
Giftige Stoffe Daten	107-91-5(Hazardous Substances Data)

Gefahreninformationscode (GHS)

2-Cyanoacetamide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White or light yellow needle crystal or powder. Slightly soluble in water, easily soluble in ethanol.
Verwenden
2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.
synthetische
Cyanoacetamide can be prepared from ethyl cyanoacetate and ammonia. Cool the ethyl cyanoacetate to below 200°C, add concentrated ammonia water to react, and the mixture turns from turbid to clear. After cooling in cold water for 20 minutes, a precipitate is precipitated. After filtration and drying, the crude product is obtained, and then the crude product of cyanoacetamide is added. In the boiling ethanol, after dissolving it, add a small amount of activated carbon for decolorization and purification, filter, cool the filtrate to separate out the precipitate, and dry it at 80-100 ℃ to obtain the fine cyanoacetamide.
Definition
2-Cyanoacetamide is an acetic amide with a nitrile functional group. It is a codon of glutamine that directs the placement of glutamine into a polypeptide.
Allgemeine Beschreibung
Cyanoacetamide is the starting reagent for vitamin B₆ synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.
läuterung methode
Crystallise the amide from MeOH/dioxane (6:4), then water and dry it over P2O5 under vacuum. [Beilstein 2 IV 1891.]

2-Cyanoacetamide Upstream-Materialien And Downstream Produkte

2-Cyanacetamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

107-91-5, 2-Cyanoacetamide Verwandte Suche:

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