L-Tryptophan Produkt Beschreibung

L-Tryptophan Struktur
73-22-3
  • CAS-Nr.73-22-3
  • Bezeichnung:L-Tryptophan
  • Englisch Name:L-Tryptophan
  • Synonyma:L-Tryptophan
    TRP;eh121;L-Trp;L-Ttp;trofan;EH 121;Eltrip;Lyphan;Tryptan;H-TRP-OH
  • CBNumber:CB3750054
  • Summenformel:C11H12N2O2
  • Molgewicht:204.23
  • MOL-Datei:73-22-3.mol
L-Tryptophan physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :289-290 °C (dec.)(lit.)
  • alpha  :-31.1 º (c=1, H20)
  • Siedepunkt: :342.72°C (rough estimate)
  • Dichte :1.34
  • Brechungsindex :-32 ° (C=1, H2O)
  • storage temp.  :Store at RT.
  • Löslichkeit :20% NH3: 0.1 g/mL at 20 °C, clear, colorless
  • Aggregatzustand :powder
  • pka :2.46(at 25℃)
  • Farbe :White to yellow-white
  • PH :5.5-7.0 (10g/l, H2O, 20℃)
  • Optische Aktivität :[α]20/D 31.5±1°, c = 1% in H2O
  • Wasserlöslichkeit :11.4 g/L (25 ºC)
  • Merck  :14,9797
  • BRN  :86197
  • Stabilität: :Stable. Incompatible with strong acids, strong oxidizing agents.
  • InChIKey :QIVBCDIJIAJPQS-VIFPVBQESA-N
  • CAS Datenbank :73-22-3(CAS DataBase Reference)
  • NIST chemische Informationen :L-Tryptophan(73-22-3)
  • EPA chemische Informationen :L-Tryptophan(73-22-3)
Sicherheit

L-Tryptophan Chemische Eigenschaften,Einsatz,Produktion Methoden

  • Chemische Eigenschaften White to off-white crystalline powder
  • Chemische Eigenschaften Appearance: white crystalline powder. Odorless, slightly bitter taste;
    Solubility: slightly soluble in water (1.14%, 25 ℃), insoluble in ethanol; soluble in dilute acid or dilute alkali. mp 289 ° C (decomposition).
    Isoelectric point: 5.89. [α] D + 2.8 (5 mol / L HCl), [α] D + 6.2 (0.5 mol / L NaOH).
    It can be colored upon long-term exposure to light. Its co-heating reaction with water will generate a small amount of indole while heating in the presence of sodium hydroxide and copper sulfate will produce a large amount of indole. It is stable upon heating together with acid in the dark, but is easily to be decomposed when heated together with other amino acids, carbohydrates and aldehydes. L-tryptophan will be completely decomposed when applying acid to break down the protein.
  • Verwenden tryptophan is one of the 21 amino acids comprising a protein. Tryptophan is a component of the skin’s natural moisturizing factors.
  • Verwenden adrenergic agonist
  • Definition ChEBI: The L-enantiomer of tryptophan.
  • Trademarks Ardeytropin;Kalma;Optimax;Sedanoct.
  • Weltgesundheitsorganisation (WHO) L-tryptophan, an essential aminoacid and precursor of serotonin, was introduced into medicine in 1963 for the treatment of depression and sleep disorders. Its effectiveness in these conditions has, however, never been convincingly demonstrated. It is also widely used in dietary supplements, parenteral nutrition preparations and dietary products for children with phenylketonuria. In 1989, reports from the USA showed an association between the consumption of L-tryptophan containing preparations and the development of eosiniphilia-myalgia syndrome (EMS), a condition characterized by intense eosinophilia, severe muscle and joint pain, swelling of the arms and legs, skin rashes and possible fever. Some of the reported cases have been fatal. Since it is not yet clear whether L-tryptophan itself or an unidentified contaminant is the cause of the EMS, many drug regulatory authorities have suspended the marketing authorization of products containing tryptophan pending further investigation, whereas others have withdrawn these products or restricted their use.
  • Allgemeine Beschreibung White powder with a flat taste. An essential amino acid; occurs in isomeric forms.
  • R-Sätze Betriebsanweisung: R33:Gefahr kumulativer Wirkungen.
    R40:Verdacht auf krebserzeugende Wirkung.
    R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
    R41:Gefahr ernster Augenschäden.
    R37/38:Reizt die Atmungsorgane und die Haut.
    R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
    R22:Gesundheitsschädlich beim Verschlucken.
  • Air & Water Reaktionen Slightly soluble in water.
  • Reaktivität anzeigen Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
  • S-Sätze Betriebsanweisung: S24/25:Berührung mit den Augen und der Haut vermeiden.
    S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
    S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  • Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition L-Tryptophan emits toxic fumes.
  • Brandgefahr Flash point data for L-Tryptophan are not available. L-Tryptophan is probably combustible.
  • Sicherheitsprofil Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
  • läuterung methode Crystallise L-tryptophan from H2O/EtOH, wash it with anhydrous diethyl ether and dry it at room temperature in a vacuum over P2O5. It sublimes at 220-230o/0.03mm with 99% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Cox & King Org Synth Coll Vol II 612 1943, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2316-2345 1961, Beilstein 22 IV 6765.]
L-Tryptophan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
L-Tryptophan Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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73-22-3, L-Tryptophan Verwandte Suche:
  • Tadalafil Impurity O
  • L-TRYPTOPHAN (USP/JP)
  • L-TRYPTOPHAN BIOULTRA, >= 99.5% (NT)
  • L-TRYPTOPHAN, REAGENT GRADE, >=98% (
  • L-Tryptophan≥ 99% (Assay)
  • L-Tryptophan,99%e.e.
  • (s)-2-amino-3-(1h-indol-3-yl)propanoic acid
  • (S)-(-)-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
  • (S)-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
  • (S)-(-)-TRYPTOPHAN
  • RARECHEM AB PP 1463
  • TRP
  • TRYPTOPHAN
  • TRYPTOPHAN, DL-
  • TRYPTOPHANE
  • TRYPTOPHAN, L-(-)-
  • TRYPTOPHAN-L
  • L-(-)-TRYPTOPHAN
  • L-TRYPTOPHAN
  • L-(-)-TRYPTOPHANE
  • L-TRYPTOPHANE
  • Indole-3-alanine
  • L-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
  • L-2-AMINO-3-INDOLEPROPIONIC ACID
  • L-(-)-2-AMINO-3-INDOLYLPROPANOIC ACID
  • L-(-)-A-AMINO-3-INDOLEPROPIONIC ACID
  • L-ALPHA-AMINO-3-INDOLEPROPIONIC ACID
  • l-alphs-amino-3-indolepropionic acid
  • L-(-)-B-3-INDOLYLALANINE
  • H-TRP-OH
  • H-L-TRP-OH
  • H-DL-TRP-OH
  • DL-A-AMINO-3-INDOLEPROPIONIC ACID
  • DL-3BETA-INDOLYLALANINE
  • DL-2-AMINO-3-INDOLEPROPIONIC ACID
  • DL-2-AMINO-3-INDOLYLPROPANOIC ACID
  • (s)-alpha-aminoindole-3-propionicacid
  • 1-beta-3-indolylalanine
  • 1beta-3-Indolylalanine
  • 1H-Indole-3-Alanine
  • 1H-Indole-3-propanoic acid, alpha-amino-, (S)-
  • 2-amino-3-indol-3-yl-propionicaci
  • 2-Amino-3-indolylpropanoic acid
  • 2-amino-3-indolylpropanoicacid
  • 3-(1h-indol-3-yl)-l-alanin
  • 3-indol-3-yl-alanin
  • 3-indol-3-ylalanine
  • nsc13119
  • Pacitron
  • Propionic acid, 2-amino-3-indol-3-yl-
  • trofan
  • tryptacin
  • tryptophane(french)
  • tryptophanum(latin)
  • L-α-Amino-3-indolepropionic acid
  • L-Tryptohan,99%
  • L-TRYPTOPHAN FEED GRADE
  • L-tryptophan USP24