Furosemid Produkt Beschreibung

Furosemide Struktur
54-31-9
  • CAS-Nr.54-31-9
  • Bezeichnung:Furosemid
  • Englisch Name:Furosemide
  • Synonyma:Furosemid
    ERIS;fusid;lasex;lasix;laxur;salix;Furix;Lazax;"mita";franyl
  • CBNumber:CB2445739
  • Summenformel:C12H11ClN2O5S
  • Molgewicht:330.74
  • MOL-Datei:54-31-9.mol
Furosemid physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :220 °C (dec.)(lit.)
  • Dichte :1.606
  • Brechungsindex :1.6580 (estimate)
  • Flammpunkt: :11 °C
  • storage temp.  :2-8°C
  • Löslichkeit :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
  • Aggregatzustand :powder
  • pka :pKa 3.8 (Uncertain)
  • Wasserlöslichkeit :Soluble in acetone, DMF or methanol. Slightly soluble in water
  • Merck  :14,4309
  • Stabilität: :Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
  • InChIKey :ZZUFCTLCJUWOSV-UHFFFAOYSA-N
  • CAS Datenbank :54-31-9(CAS DataBase Reference)
  • EPA chemische Informationen :Benzoic acid, 5-(aminosulfonyl)-4-chloro- 2-((2-furanylmethyl)amino)- (54-31-9)
Sicherheit

Furosemide Chemische Eigenschaften,Einsatz,Produktion Methoden

  • R-Sätze Betriebsanweisung: R61:Kann das Kind im Mutterleib schädigen.
    R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
    R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
    R11:Leichtentzündlich.
    R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  • S-Sätze Betriebsanweisung: S7:Behälter dicht geschlossen halten.
    S16:Von Zündquellen fernhalten - Nicht rauchen.
    S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
    S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
    S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
    S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
    S22:Staub nicht einatmen.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
    S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  • Chemische Eigenschaften white to light yellow crystal powde
  • Verwenden diuretic, antihypertensive
  • Verwenden Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.
  • Verwenden This compound belongs to the aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
  • Verwenden An inhibitor of NKCC and a GABAA receptor antagonist.
  • Definition A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration and anti-hypertensive agent.
  • Trademarks Lasix (Sanofi Aventis).
  • Allgemeine Beschreibung Odorless white to slightly yellow crystalline powder. A diuretic drug. Almost tasteless.
  • Air & Water Reaktionen Light sensitive. Air sensitive. Slightly soluble in water.
  • Reaktivität anzeigen Furosemide may undergo hydrolysis at sufficiently low pH. The pH of aqueous solutions should be maintained in the basic range to prevent hydrolysis. Alcohol has been shown to improve the stability of Furosemide. Incompatible with strong oxidizing agents .
  • Hazard Poison; moderately toxic; teratogen; questionable carcinogen; mutagen.
  • Brandgefahr Flash point data for Furosemide are not available; however, Furosemide is probably combustible.
  • Biologische Aktivität Loop diuretic that inhibits the Na + /2Cl - /K + (NKCC) cotransporter. Also acts as a non-competitive antagonist at GABA A receptors with ~ 100-fold greater selectivity for α 6-containing receptors than α 1-containing receptors.
  • Sicherheitsprofil Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by intravenous route: change in the sensitivity of the ear to sound, tinnitus, unspecified effects on the heart, constriction of the arteries, a decrease in urine volume, interstitial nephritis, metabolic alkalosis, pulse rate decrease, fall in blood pressure. Ingestion can damage the liver. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and SOx.
  • Veterinary Drugs and Treatments Furosemide is used for its diuretic activity in all species. It is used in small animals for the treatment of congestive cardiomyopathy, pulmonary edema, hypercalcuric nephropathy, uremia, as adjunctive therapy in hyperkalemia and, occasionally, as an antihypertensive agent. In cattle, it is approved for use for the treatment of post-parturient udder edema. It has been used to help prevent or reduce epistaxis (exercise-induced pulmonary hemorrhage; EIPH) in racehorses.
Furosemide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Furosemid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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54-31-9, Furosemide Verwandte Suche:
  • FUROSEMIDE METHANOL SOLUTION
  • FUROSEMIDE, RELATED COMPOUND B 4-CHLORO-5-SULFAMOYLANTHRANILIC ACID USP STANDARD
  • FUROSEMIDE, EP STANDARD
  • FUROSEMIDE, IMP. A (EP):2-CHLORO-4-FURFURYLAMINO-5-SULPHAMOYLBENZOIC ACID MM(CRM STANDARD)
  • FUROSEMIDE, IMP. B (EP): 2,4-DICHLORO-5-SULPHAMOYLBENZOIC ACID MM(CRM STANDARD)
  • FUROSEMIDE, MM(CRM STANDARD)
  • FUROSEMIDE, WHO(CRM STANDARD)
  • FUROSEMIDE, IMP. C (EP): 2-AMINO-4-CHLORO-5-SULPHAMOYLBENZOIC ACID MM(CRM STANDARD)
  • FUROSEMIDE, IMPURITY A2-CHLORO-4-(FURFURYLAMINO)-5-SULPHAMOYLBENZOIC ACID EP STANDARD
  • FUROSEMIDE, USP STANDARD
  • FUROSEMIDE, BP STANDARD(CRM STANDARD)
  • FUROSEMIDE, RELATED COMPOUND A 2-CHLORO-4-N-FURFURYLAMINO-5-SULFAMOYLBENZOIC ACID USP STANDARD
  • FUROSEMIDE UNLABELED 1.0 MG/ML IN METHANOL
  • FrusemideFrusemide
  • 4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoic acid
  • Furosemide for peak identification
  • ANTI-TM173(C-TERMINAL) antibody produced in rabbit
  • ERIS
  • TMEM173
  • Transmembrane protein 173
  • Furosemide (furosemide)
  • LABOTEST-BB LT00244801
  • FUROSEMID
  • FUROSEMIDE
  • FRUSEMIDE
  • 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
  • 4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID
  • 5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
  • 5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID
  • 4 CHLORO 2 FURAN 2 YL METHYL AMINO 5 SUL
  • "mita"
  • 4-chloro-n-(2-furylmethyl)-5-sulfanoylanthranilicacid
  • 4-chloro-n-furfuryl-5-sulfamoyl-anthranilicaci
  • 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)-benzoicaci
  • 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-benzoicaci
  • 5-(Aminosulfonyl)-4-chloro-2-[2-(furamyl-methyl)amino]-benzoicacid
  • aluzine
  • aquasin
  • arasemide
  • chlor-n-(2-furylmethyl)-5-sulfamylanthranilsaeure
  • diurolasa
  • endural
  • franyl
  • frusemin
  • furanthril
  • furanthryl
  • furantril
  • furose
  • furosemide"mita"
  • furosemidu
  • furoside
  • fursemid
  • fursemide
  • fusid
  • hydrex
  • hydroled
  • lasex
  • lasiletten