Furfurylamin

Bezeichnung:Furfurylamin

CAS-Nr617-89-0

Englisch Name:Furfurylamine

CBNumberCB0364366

SummenformelC5H7NO

Molgewicht97.12

MOL-Datei617-89-0.mol

Synonyma

Furfurylamin

Furfurylamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	−70 °C(lit.)
Siedepunkt	145-146 °C(lit.)
Dichte	1.099 g/mL at 25 °C(lit.)
Dampfdichte	3.35 (vs air)
Dampfdruck	4 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.490(lit.)
Flammpunkt	116 °F
storage temp.	Store below +30°C.
Löslichkeit	Chloroform, Ethyl Acetate (Slightly)
Aggregatzustand	Liquid
pka	9.12±0.29(Predicted)
Farbe	Clear colorless to yellow-brown
PH	11.6 (100g/l, H2O, 20℃)
Geruch (Odor)	strong fishy ammonia-like odor
Explosionsgrenze	1.8%(V)
Wasserlöslichkeit	soluble
Sensitive	Air Sensitive
BRN	1614
Stabilität	Volatile
LogP	0.37
CAS Datenbank	617-89-0(CAS DataBase Reference)
NIST chemische Informationen	2-Furanmethanamine(617-89-0)
EPA chemische Informationen	Furfurylamine (617-89-0)

Sicherheit

Kennzeichnung gefährlicher	C,F,Xi
R-Sätze:	10-21/22-34-20/21/22
S-Sätze:	26-36/37/39-45-23-16
RIDADR	UN 2526 3/PG 3
WGK Germany	3
RTECS-Nr.	LU9275000
Selbstentzündungstemperatur	350 °C DIN 51794
Hazard Note	Harmful/Corrosive/Flammable
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29321900
Toxizität	LD50 orally in Rabbit: 200 - 2000 mg/kg LD50 dermal Rat 100 mg/kg

Gefahreninformationscode (GHS)

Furfurylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R10:Entzündlich.
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
R34:Verursacht Verätzungen.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Furfurylamine is a colorless to light yellow aromatic amine in liquid form with an ammonia odor. Miscible with water, soluble in ethanol, ether. Deteriorates in air by absorbing carbon dioxide. Derived from furfural based on corn cobs, this green chemistry has proven useful in engine cleaners, and as an intermediate for pharmaceutical, industrial and agricultural chemicals.
Verwenden
Furfurylamine is used as a water miscible solvent and as an intermediate in manufacturing pharmaceuticals like diuretics, antihypertensive, and antiseptic agents.
Furfurylamine also has use in the synthesis of Barmastine.
2-Furfurylamine is used in the synthesis of 2-Amino-N-(2-furylmethyl)propanamide, as a novel alanylglycine equivalent synthesized by bacilysin synthetase.
synthetische
Synthesis of furfurylamine by Zn/HCl system: To a solution of furfuryloxime (2g, 18mmol) in hydrochloric acid (6.0M, 24ml) was added drop-wise zinc dust (4.71g, 72mmol), and the resultant solution was stirred at room temperature for 2 h. To the resulting slurry was added drop-wise a solution of ammonia (30%, 5.1 mL) and sodium hydroxide (6M, 24mL), the mixture was heated to 60° and stirred for 15mn. After, the resultant solution was cooled and filtered. Then, the mother liquid was extracted with cyclohexane, dried over anhydrous sodium sulfate and filtered. The solvent was removed under vacuum to afford the furfurylamine as a yellow liquid without further purification in 96% of yield (1.68g). The purity determined by NMR was found to be superior to 95%.
SIMPLE, NOVEL SYNTHESIS OF FURFURYLAMINE FROM FURFURAL BY ONE-POT REDUCTIVE AMINATION IN WATER USING ZINC METAL
Allgemeine Beschreibung
Furfurylamine appears as a colorless liquid. About the same density as water. Used as a corrosion inhibitor and to make soldering flux.
Air & Water Reaktionen
Highly flammable. Soluble in water.
Reaktivität anzeigen
Amines, such as Furfurylamine, are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Hazard
Flammable, moderate fire risk.
Health Hazard
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Brandgefahr
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
Sicherheitsprofil
Poison by intraperitoneal route. A skin,eye, and mucous membrane irritant. A dangerous fire hazard when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO2, drp chemical. When heated to decomposition it emits toxic fumes of NOx. See also MINES.

Furfurylamine Upstream-Materialien And Downstream Produkte

Furfurylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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