Description
Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.
Chemical Properties
White to off-white crystalline powder
Uses
An antibiotic related to penicillin
Uses
Penicillin antibacterial.
Definition
ChEBI: Piperacillin sodium is an organic sodium salt. It contains a piperacillin(1-).
Brand name
Pipracil (Wyeth).
Synthesis
is typically prepared from palladium(II) chloride. Step 1: Preparation of Li₂PdCl₄ solution: Stir palladium chloride, lithium chloride and ethanol overnight under nitrogen protection, then filter. Step 2: Preparation of Tris(dibenzylideneacetone)dipalladi
storage
Store at 2-8°C, sealed storage, away from moisture
