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50-23-7

Name Hydrocortisone
CAS 50-23-7
EINECS(EC#) 200-020-1
Molecular Formula C21H30O5
MDL Number MFCD00011654
Molecular Weight 362.46
MOL File 50-23-7.mol

Chemical Properties

Appearance crystalline white powder
Melting point  211-214 °C(lit.)
alpha  166 º (c=1, C2H5OH 25 ºC)
Boiling point  414.06°C (rough estimate)
density  1.0812 (rough estimate)
refractive index  1.6120 (estimate)
Fp  220°C
storage temp.  −20°C
solubility  H2O: 100 mg/mL
form  powder
color  White
Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Water Solubility  319.7mg/L(25 ºC)
Decomposition  220 ºC
Merck  14,4787
BRN  1354819
Contact allergens
Hydrocortisone is the principal glucocorticoid hor- mone produced by the adrenal cortex and is used topi- cally or systemically. It belongs to the allergenic A group. Marker of allergy is tixocortol pivalate.
LogP 1.610
CAS DataBase Reference 50-23-7(CAS DataBase Reference)
NIST Chemistry Reference Hydrocortisone(50-23-7)
EPA Substance Registry System 50-23-7(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R63:Possible risk of harm to the unborn child.
R62:Possible risk of impaired fertility.
R40:Limited evidence of a carcinogenic effect.
Safety Statements 
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S22:Do not breathe dust .
WGK Germany  3
RTECS  GM8925000
TSCA  Yes
HS Code  29372100
Safety Profile
Poison by
Hazardous Substances Data 50-23-7(Hazardous Substances Data)
Toxicity
LD50 subcutaneous in mouse: > 500mg/kg

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