Стиралилацетат

Описание

α-Methylbenzyl acetate has an intensive green odor suggestive of gardenia with a bitter, acrid taste, interesting on dilution. May be prepared by acetylation of methyl phenyl carbinol; from benzaldehyde by reacting with magnesium methyl bromide and subsequent acetylation; from 1-bromoethylbenzene and silver acetate in acetic acid.

Химические свойства

CLEAR COLOURLESS TO PALE YELLOWISH LIQUID

Вхождение

Reported found in gardenia flower oil and avocado.

Использование

Styralyl Acetate is a freshening compound with Alkoxylated Phenols.
Styralyl acetate finds extensive use in flavor compositions, particularly the "sharp"-fruity types, Pineapple, Apricot, Gooseberry, Apple, but also in Plum, Peach and many berry or fruit complexes.
The concentration is about 1 to 30 ppm in the finished product.

Подготовка

By acetylation of methyl phenyl carbinol; from benzaldehyde by reacting with magnesium methyl bromide and subse quent acetylation; from 1-bromoethylbenzene and silver acetate in acetic acid.

Метаболизм

Although no published data exist on the metabolism of methylphenylcarbinyl acetate, it is likely that hydrolysis to the carbinol and acetic acid is the initial step. Williams (1959) reports studies in which 50% of a dose of (±)-methylphenylcarbinol given to rabbits was excreted as the glucuronide in the urine within 24 hr. There was some evidence of oxidation and demethylation, as mandelic and hippuric acids were found in the urine. Previously, El Masry, Smith