ω-Pentadecalactone has an extraordinarily persistent, musk-like odor.
white crystalline low melting solid
Cyclopentadecanolide occurs in small quantities in,
for example, angelica root oil. It forms colorless crystals (mp 37–38°C) with a
delicate, musk-like odor.
Originally reported found in the essential oil from angelica roots.
Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.
Pentadecanolide may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization. It may be employed as starting reagent for the synthesis of terminally-branched iso-fatty acids (iso-C15-C17).
As a fixative in perfumery.
ChEBI: Cyclopentadecanolide is a macrolide.
The main industrial syntheses start from compounds produced
from cyclododecatriene: either by ring expansion of cyclododecanone or
by depolymerization of polyesters of 15-hydroxypentadecanoic acid (from
1,12-dodecanediol).
Taste characteristics at 75 ppm: vanilla bean, powdery helioropine, creamy and licorice.
Pentadecanolide is one of the major components, isolated from the root of Angelica archangelica L., species. It is a synthetic musk, which exists as a widespread contaminant in the environment.
Flammability and Explosibility
Non flammable
Macrolide® (Symrise), Exaltolide®, Exaltolide®Total (Firmenich),
Pentalide (Soda Aromatic).
It has been recrystallised from MeOH (4 parts) at -15o. [Hundieck