Chemical Properties
ω-Pentadecalactone has an extraordinarily persistent, musk-like odor.
Chemical Properties
white crystalline low melting solid
Chemical Properties
Cyclopentadecanolide occurs in small quantities in,
for example, angelica root oil. It forms colorless crystals (mp 37–38°C) with a
delicate, musk-like odor.
Occurrence
Originally reported found in the essential oil from angelica roots.
Uses
Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.
Uses
Pentadecanolide may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization. It may be employed as starting reagent for the synthesis of terminally-branched iso-fatty acids (iso-C
15-C
17).
Uses
As a fixative in perfumery.
Definition
ChEBI: Cyclopentadecanolide is a macrolide.
Preparation
The main industrial syntheses start from compounds produced
from cyclododecatriene: either by ring expansion of cyclododecanone or
by depolymerization of polyesters of 15-hydroxypentadecanoic acid (from
1,12-dodecanediol).
Aroma threshold values
Detection: 1 to 4 ppb
Taste threshold values
Taste characteristics at 75 ppm: vanilla bean, powdery helioropine, creamy and licorice.
General Description
Pentadecanolide is one of the major components, isolated from the root of
Angelica archangelica L., species. It is a synthetic musk, which exists as a widespread contaminant in the environment.
Flammability and Explosibility
Non flammable
Trade name
Macrolide® (Symrise), Exaltolide®, Exaltolide®Total (Firmenich),
Pentalide (Soda Aromatic).
Purification Methods
It has been recrystallised from MeOH (4 parts) at -15o. [Hundieck