α-Angelica lactone has a sweet, herbaceous odor reminiscent of tobacco.
clear colorless to straw yellow liquid
Reported found in grape, white bread, soy bean and licorice.
alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors.
By dry distillation of levulinic acid
alpha-Angelica lactone finds occasional use in the
reconstitution of essential oils. lts intensely
sweet-herbaceous, almost tobacco-like odor
makes this chemical interesting for application
in new fragrance types. However, it would be
wise to investigate its pharmacological and
dermatological properties first.
ChEBI: Alpha-angelica lactone is an angelica lactone and a butenolide. It is functionally related to a but-3-en-4-olide. It is a tautomer of a beta-angelica lactone.
Taste characteristics at 100 ppm: sweet, creamy, coconut, vanilla hay and coumarin-like nuances
α-Angelica lactone, a cyclic lactone that occurs naturally in tobacco, is generally used in tobacco flavoring.
Plant-derived cancer chemopreventive agent. Increases the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver.
Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits acrid smoke and irritating fumes.
