CLEAR PALE YELLOW TO BROWN LIQUID.
soluble in water, alcohol, ethers, and most organic solvents.
Tris(2-(2-methoxyethoxy)ethyl)amine was used:
in oxidation of arylmethanols under phase-transfer conditions;
as cryptand during phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine;
as phase-transfer catalyst in synthesis of 1,3-dideaza-2′-deoxyadenosine and related benzimidazole 2′-deoxyribonucleosides.
Tris(2-(2-methoxyethoxy)ethyl)amine was prepared by the reaction of 2-(2-methoxy-ethoxy)ethanol with a mixture of ammonia gas and hydrogen gas in the presence of catalytic amounts of Raney nickel.